ID A0A337SFP2_FELCA Unreviewed; 170 AA.
AC A0A337SFP2;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Pre-mRNA-splicing regulator WTAP {ECO:0000256|ARBA:ARBA00017540};
DE AltName: Full=Female-lethal(2)D homolog {ECO:0000256|ARBA:ARBA00033097};
DE AltName: Full=WT1-associated protein {ECO:0000256|ARBA:ARBA00032703};
DE AltName: Full=Wilms tumor 1-associating protein {ECO:0000256|ARBA:ARBA00032336};
GN Name=WTAP {ECO:0000313|Ensembl:ENSFCAP00000044538.1,
GN ECO:0000313|VGNC:VGNC:84872};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000044538.1, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000044538.1, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000044538.1,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000044538.1, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000044538.1,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000044538.1}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000044538.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the fl(2)d family.
CC {ECO:0000256|ARBA:ARBA00010313}.
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DR EMBL; AANG04000169; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_011280857.1; XM_011282555.2.
DR AlphaFoldDB; A0A337SFP2; -.
DR SMR; A0A337SFP2; -.
DR Ensembl; ENSFCAT00000065600.2; ENSFCAP00000044538.1; ENSFCAG00000002844.6.
DR VGNC; VGNC:84872; WTAP.
DR GeneTree; ENSGT00390000013931; -.
DR Proteomes; UP000011712; Chromosome B2.
DR Bgee; ENSFCAG00000002844; Expressed in embryonic head and 10 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0080009; P:mRNA methylation; IEA:InterPro.
DR GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IEA:InterPro.
DR InterPro; IPR033757; WTAP.
DR PANTHER; PTHR15217:SF1; PRE-MRNA-SPLICING REGULATOR WTAP; 1.
DR PANTHER; PTHR15217; WILMS' TUMOR 1-ASSOCIATING PROTEIN; 1.
DR Pfam; PF17098; Wtap; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000011712}.
FT COILED 121..148
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 170 AA; 19892 MW; C145B0312DE743A6 CRC64;
MTNEEPLPKK VRLSETDFKV MARDELILRW KQYEAYVQAL EGKYTDLNSN DVTGLRESEE
KLKQQQQESA RRENILVMRL ATKEQEMQEC TTQIQYLKQV QQPSVAQLRS TMVDPAINLF
FLKMKGELEQ TKDKLEQAQN ELSAWKFTPD RGLMASDYSE EVATSEKFPF
//
