ID A0A337SH11_FELCA Unreviewed; 433 AA.
AC A0A337SH11;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=RUN and SH3 domain containing 1 {ECO:0000313|Ensembl:ENSFCAP00000045231.2};
GN Name=RUSC1 {ECO:0000313|Ensembl:ENSFCAP00000045231.2,
GN ECO:0000313|VGNC:VGNC:107934};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000045231.2, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000045231.2, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000045231.2,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000045231.2, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000045231.2,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000045231.2}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000045231.2};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AANG04002876; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A337SH11; -.
DR PaxDb; 9685-ENSFCAP00000017910; -.
DR Ensembl; ENSFCAT00000055419.2; ENSFCAP00000045231.2; ENSFCAG00000024900.4.
DR VGNC; VGNC:107934; RUSC1.
DR GeneTree; ENSGT00900000141033; -.
DR Proteomes; UP000011712; Chromosome F1.
DR Bgee; ENSFCAG00000024900; Expressed in prefrontal cortex and 10 other cell types or tissues.
DR CDD; cd17701; RUN_RUSC1; 1.
DR Gene3D; 1.20.58.900; -; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR004012; Run_dom.
DR InterPro; IPR037213; Run_dom_sf.
DR InterPro; IPR047341; RUN_RUSC1.
DR InterPro; IPR047343; RUSC1_2.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR15591:SF11; AP-4 COMPLEX ACCESSORY SUBUNIT RUSC1; 1.
DR PANTHER; PTHR15591; RUN AND SH3 DOMAIN CONTAINING; 1.
DR Pfam; PF02759; RUN; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00593; RUN; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF140741; RUN domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50826; RUN; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 53..197
FT /note="RUN"
FT /evidence="ECO:0000259|PROSITE:PS50826"
FT DOMAIN 375..433
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 237..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 281..307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 356..377
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 433 AA; 45700 MW; 2C54B66D64EA3BC2 CRC64;
MAETQGGAGQ LQEQKKGLLI AVSASVDKII SHFGAARNLV QKAQLGDSRL SPDVGHLVLT
TLCPALHALV ADGLKPFRKD LITGQRRSSP WSVVEASVKP GSGTRSLGTL YSQVSRLAPL
SSSRSRFHAF ILGLLNTKQL ELWFSSLQED AGLLSLLYLP TGFFSLARGG CPALTTELLL
LLQPLSVLTF HLDLLFEHHH HLPLGPPPAA PAPGSPPALQ HTVRAVLHWG GRLAQSLRGA
SGETPPGPSA PASPPAPGGW WEQLTQASRV YASGSGEGFP LPRWRSWRPS GTAEGAQDGP
LPAEEAAPGR GVWLGRLFGV PGGVTEADGG ALKSRRPSSW LPPTVSVLAL VRRAPPPETL
SSPEEPEAAA PSAPQTHRAV RALCDHTAAG PGQLSFRRGE VLRVLGTVDE DWLRCGRDGT
EGLVPVGYTS LVL
//
