ID A0A337SPS5_FELCA Unreviewed; 617 AA.
AC A0A337SPS5;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Thioredoxin domain containing 2 {ECO:0000313|Ensembl:ENSFCAP00000049390.2};
GN Name=TXNDC2 {ECO:0000313|Ensembl:ENSFCAP00000049390.2,
GN ECO:0000313|VGNC:VGNC:107730};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000049390.2, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000049390.2, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000049390.2,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000049390.2, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000049390.2,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000049390.2}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000049390.2};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AANG04003548; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A337SPS5; -.
DR STRING; 9685.ENSFCAP00000049390; -.
DR Ensembl; ENSFCAT00000055473.2; ENSFCAP00000049390.2; ENSFCAG00000041623.2.
DR VGNC; VGNC:107730; TXNDC2.
DR GeneTree; ENSGT00940000163147; -.
DR InParanoid; A0A337SPS5; -.
DR OMA; PNFPAKF; -.
DR Proteomes; UP000011712; Chromosome D3.
DR Bgee; ENSFCAG00000041623; Expressed in testis and 8 other cell types or tissues.
DR CDD; cd02947; TRX_family; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR10438; THIOREDOXIN; 1.
DR PANTHER; PTHR10438:SF107; THIOREDOXIN DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF00085; Thioredoxin; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011712}.
FT DOMAIN 479..617
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 215..373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 451..491
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..264
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..358
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 462..487
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 617 AA; 66737 MW; 4DAA75E185399CE5 CRC64;
MDKEQEVESD RAGTPEDPNM SPEKQEADQG DVNESPLLQG LSSHVTPLVP EFLDTAHIQE
TASASEADNI QHMPAKQSKG PQLKVIFPPA QGGNIFNFSA MTMQPKQAGT PGFSAKIIPR
EQGSIPNSLA KMILPRQADT PNSPEKIIPL KQAGISNPLA KPIPPKQANI PSFSAKSISP
KQVDTPSFSA KIIQPKHGSI PNSSAKMILP KHGNALNFPT KITPPKQADI PSSPAKSIPP
KQAGTPNSPA KTIPPKQTDT PNFSGKIILP KDSDTPNPSE ERIPPKQADT PNSPAKSIPP
KQADTPNSPA KSIPPKQTDT PNFSGKVILP KESDTPNPSE ERIPPKQADS SNSSEKIIAP
KHGDTPSSSE KTTLLQEDGM STSLEKNIPP KQDNIPMSLA KTILPKQGKS LKFLAKSILP
KQANTPKFSA KPFLSKQINS PKLLVKSTLS KHIPNPKSSE ENILPREGDT KCSEDSIQPK
EGDIPKSSKE AIPPIEGDVL KASGSMELLE VDLVKMILSK EDFELALREA GERLVAVDFS
ATWCGPCRTI KPLFHSLSVK YEDVVFLEVD ADECDELVKD LEIMCIPTFQ FYKKEEKVGE
FCGAVTEKLE AIIAELK
//
