ID A0A337SS35_FELCA Unreviewed; 619 AA.
AC A0A337SS35;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Baculoviral IAP repeat containing 3 {ECO:0000313|Ensembl:ENSFCAP00000050755.2};
GN Name=BIRC3 {ECO:0000313|Ensembl:ENSFCAP00000050755.2};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000050755.2, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000050755.2, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000050755.2,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000050755.2, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000050755.2,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000050755.2}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000050755.2};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the IAP family. {ECO:0000256|ARBA:ARBA00006672}.
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DR EMBL; AANG04000690; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003992351.1; XM_003992302.4.
DR AlphaFoldDB; A0A337SS35; -.
DR PaxDb; 9685-ENSFCAP00000018745; -.
DR Ensembl; ENSFCAT00000066806.2; ENSFCAP00000050755.2; ENSFCAG00000041774.2.
DR GeneTree; ENSGT00940000154175; -.
DR OrthoDB; 383715at2759; -.
DR Proteomes; UP000011712; Chromosome D1.
DR Bgee; ENSFCAG00000041774; Expressed in spleen and 11 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0031398; P:positive regulation of protein ubiquitination; IEA:UniProt.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR CDD; cd00022; BIR; 3.
DR CDD; cd08329; CARD_BIRC2_BIRC3; 1.
DR CDD; cd16713; RING-HC_BIRC2_3_7; 1.
DR CDD; cd14394; UBA_BIRC2_3; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR InterPro; IPR001370; BIR_rpt.
DR InterPro; IPR048875; BIRC2-3-like_UBA.
DR InterPro; IPR041933; BIRC2/BIRC3_UBA.
DR InterPro; IPR001315; CARD.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR001841; Znf_RING.
DR PANTHER; PTHR10044:SF79; BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR10044; INHIBITOR OF APOPTOSIS; 1.
DR Pfam; PF00653; BIR; 3.
DR Pfam; PF21290; BIRC2-3-like_UBA; 1.
DR Pfam; PF00619; CARD; 1.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00238; BIR; 3.
DR SMART; SM00114; CARD; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR SUPFAM; SSF57924; Inhibitor of apoptosis (IAP) repeat; 3.
DR PROSITE; PS01282; BIR_REPEAT_1; 2.
DR PROSITE; PS50143; BIR_REPEAT_2; 3.
DR PROSITE; PS50209; CARD; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 454..544
FT /note="CARD"
FT /evidence="ECO:0000259|PROSITE:PS50209"
FT DOMAIN 572..607
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 619 AA; 69797 MW; 4203436E12FB1E15 CRC64;
MHKTTSQRLV PGSSCQRIKS TMEDSTIFTN RTVGSKQRIQ YDLSCELYRM STYSTFPAGV
PVSERSLARA GFYYTGVKDK VRCFCCGLML DNWKHGDSPI EKHKQLYPSC SFIHSLVSLT
SLESTSKNAS PLRNSFPHLL SPTSEHGGTF SGSHSNLSPN SVNSRALEDF SPLRTNPYSY
AMSTEEARFL TYHMWPLTFL SPSELARAGF YYIGPGDKVA CFACGGTLSN WEPKDDALSE
HRRHFPNCPF LENSLETLRF SISNLSMQTH AARLRTFVCW PSSVPVQPEQ LASAGFYYVG
RNDDVKCFCC DGGLRCWESG DDPWVEHAKW FPRCEFLIRM KGQDFVDEIQ ARYPHLLEQL
LSTSDTPGDE NTDPPIVHFG PGENSSEDAV MMNTPVVKAA LEMGFSRNLV KQTVQSKILT
SGENYKTVSD IVLALLDAED ETREEEKERQ TEELASDDLS LIRRNRMALF QQLTCVLPIL
DNLLKANVIN KQEHDIIKQK TQIPLQAREL IDTVLVKGNA AANIFKSCLK EIDPTLYKNL
FVDKNMKYIP TEDVSGLSLE EQLRRLQEER TCKVCLDREV SIVFIPCGHL VVCQDCAPSL
RKCPICRGII KGTVRTFLS
//
