ID A0A337STY3_FELCA Unreviewed; 461 AA.
AC A0A337STY3;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Potassium channel tetramerization domain containing 17 {ECO:0000313|Ensembl:ENSFCAP00000049322.2};
GN Name=KCTD17 {ECO:0000313|Ensembl:ENSFCAP00000049322.2,
GN ECO:0000313|VGNC:VGNC:63057};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000049322.2, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000049322.2, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000049322.2,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000049322.2, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000049322.2,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000049322.2}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000049322.2};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
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DR EMBL; AANG04003655; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A337STY3; -.
DR STRING; 9685.ENSFCAP00000049322; -.
DR Ensembl; ENSFCAT00000057319.2; ENSFCAP00000049322.2; ENSFCAG00000001070.5.
DR VGNC; VGNC:63057; KCTD17.
DR GeneTree; ENSGT00940000161746; -.
DR InParanoid; A0A337STY3; -.
DR Proteomes; UP000011712; Chromosome B4.
DR Bgee; ENSFCAG00000001070; Expressed in prefrontal cortex and 9 other cell types or tissues.
DR GO; GO:0031463; C:Cul3-RING ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0097602; F:cullin family protein binding; IBA:GO_Central.
DR GO; GO:0045724; P:positive regulation of cilium assembly; IBA:GO_Central.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR CDD; cd18391; BTB_POZ_KCTD17; 1.
DR Gene3D; 3.30.70.2000; -; 1.
DR Gene3D; 6.10.140.750; -; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR PANTHER; PTHR14958:SF24; BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD17; 1.
DR PANTHER; PTHR14958; POTASSIUM CHANNEL TETRAMERISATION DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF02214; BTB_2; 1.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011712}.
FT DOMAIN 47..148
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 214..323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 408..431
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 214..231
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 252..266
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 287..323
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 461 AA; 50289 MW; 31D3252428E4011E CRC64;
MPGARYLPAP SRRARRMQTP GRAGRMEAGE AAPPAGAGGR APGGWGKWVR LNVGGTVFLT
TRQTLCREQK SFLSRLCQGE ELQSDRDETG AYLIDRDPTY FGPILNFLRH GKLVLDKDMA
EEGVLEEAEF YNIGPLIRII KDRMEEKDYP VTQVPPKHVY RVLQCQEEEL TQMVSTMSDG
WRFEQLVNIG SSYNYGNEDQ AEFLCVVSKE LYTSPHGLSS ESSRKTKPSP PRSPLTFSPS
RHRRLLRFPR EAPPHLHPPL PPPGSHLHPA SSLSAPVRVS SLPAHASIPG PPRPPPPAPS
TQAPRPPRIP EPPACRLPRP LWRLPPPGLG TRVVAASPWR RPAPPGTPEA GPPRPAPPVL
AAAAASRFLL AGPRLHPSGL RLRLQRGLLL LGAPRPPPQS RHPCCYKPEA PGSEESRVQP
SGAATRRRCR GAPCRTQRTA LAWAGARGAA LGSCDSTVRC G
//
