ID A0A337SVK0_FELCA Unreviewed; 276 AA.
AC A0A337SVK0;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Coiled-coil domain-containing protein 25 {ECO:0000256|ARBA:ARBA00016700};
GN Name=CCDC25 {ECO:0000313|Ensembl:ENSFCAP00000050656.1,
GN ECO:0000313|VGNC:VGNC:78463};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000050656.1, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000050656.1, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000050656.1,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000050656.1, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000050656.1,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000050656.1}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000050656.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBUNIT: Interacts (via cytoplasmic region) with ILK.
CC {ECO:0000256|ARBA:ARBA00024214}.
CC -!- SIMILARITY: Belongs to the CCDC25 family.
CC {ECO:0000256|ARBA:ARBA00008998}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AANG04001605; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A337SVK0; -.
DR STRING; 9685.ENSFCAP00000050656; -.
DR PaxDb; 9685-ENSFCAP00000013379; -.
DR Ensembl; ENSFCAT00000063529.2; ENSFCAP00000050656.1; ENSFCAG00000037880.3.
DR VGNC; VGNC:78463; CCDC25.
DR GeneTree; ENSGT00390000004380; -.
DR InParanoid; A0A337SVK0; -.
DR OMA; CDERSHF; -.
DR Proteomes; UP000011712; Chromosome B1.
DR Bgee; ENSFCAG00000037880; Expressed in embryonic head and 10 other cell types or tissues.
DR GO; GO:0012505; C:endomembrane system; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR GO; GO:2000147; P:positive regulation of cell motility; IEA:Ensembl.
DR InterPro; IPR039730; Jlp2/Ccd25.
DR InterPro; IPR008532; NFACT_RNA-bd.
DR PANTHER; PTHR13049:SF2; COILED-COIL DOMAIN-CONTAINING PROTEIN 25; 1.
DR PANTHER; PTHR13049; DUF814-RELATED; 1.
DR Pfam; PF05670; NFACT-R_1; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000011712}.
FT DOMAIN 79..180
FT /note="NFACT RNA-binding"
FT /evidence="ECO:0000259|Pfam:PF05670"
FT REGION 215..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..254
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 257..276
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 276 AA; 31925 MW; 060ABE0000197020 CRC64;
MAPTGWRYDA TRRPPEVSEE FRGTGGLRAS GILVSCELSA PTPRWSRCAA AGIMVFYFTS
SSVKTHAILL LLSLLVKVNS SAYTIYMGKD KYENEDLIKY GWPEDIWFHV DKLSSAHVYL
RLHKGEKIED IPKEVLMDCA HLVKANSIQG CKMNNVNVVY TPWSNLKKTA DMDVGQIGFH
RQKDVKIVTV EKKVNEILNR LEKTRMERFP DLAAEKECRD REERNEKKAQ IQEMKRREKE
EMKKKREMDE LRSYSSLMKV ENMSSNQDGN DSDEFM
//
