ID A0A340W938_LIPVE Unreviewed; 743 AA.
AC A0A340W938;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Threonine synthase-like 1 {ECO:0000313|RefSeq:XP_007445928.1};
GN Name=THNSL1 {ECO:0000313|RefSeq:XP_007445928.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007445928.1};
RN [1] {ECO:0000313|RefSeq:XP_007445928.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR604450-51};
CC -!- SIMILARITY: Belongs to the threonine synthase family.
CC {ECO:0000256|ARBA:ARBA00005517}.
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DR RefSeq; XP_007445928.1; XM_007445866.1.
DR AlphaFoldDB; A0A340W938; -.
DR STRING; 118797.A0A340W938; -.
DR GeneID; 103086113; -.
DR KEGG; lve:103086113; -.
DR CTD; 79896; -.
DR InParanoid; A0A340W938; -.
DR OrthoDB; 5309433at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR CDD; cd00464; SK; 1.
DR CDD; cd01560; Thr-synth_2; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.90.1380.10; Threonine synthase, N-terminal domain; 1.
DR HAMAP; MF_00109; Shikimate_kinase; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR031322; Shikimate/glucono_kinase.
DR InterPro; IPR000623; Shikimate_kinase/TSH1.
DR InterPro; IPR029144; Thr_synth_N.
DR InterPro; IPR037158; Thr_synth_N_sf.
DR InterPro; IPR004450; Thr_synthase-like.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR NCBIfam; TIGR00260; thrC; 1.
DR PANTHER; PTHR43515; THREONINE SYNTHASE-LIKE 1; 1.
DR PANTHER; PTHR43515:SF1; THREONINE SYNTHASE-LIKE 1; 1.
DR Pfam; PF01202; SKI; 1.
DR Pfam; PF14821; Thr_synth_N; 1.
DR PRINTS; PR01100; SHIKIMTKNASE.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR604450-51};
KW Reference proteome {ECO:0000313|Proteomes:UP000265300}.
FT DOMAIN 246..318
FT /note="Threonine synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14821"
FT MOD_RES 351
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR604450-51"
SQ SEQUENCE 743 AA; 83023 MW; 0A90DCBF8A1354A6 CRC64;
MLYLNRCQHL KQITQKCFSS THVKTDKHAQ LFLSRTFALA ELRKSWHSIY SLVGDKNIIL
MGPPGAGKTT VGRIIGQKLG CCVIDVDDDI LEKTWNMSVS EKLQDVGNEQ FLEEEGKAVL
NFSASGSVIS LTGSNPMHDA SMRHLKKNGI IVYLDVPPID IVSRLKLMKI DRIVGQNSET
SMKDLLKFRR QYYKKWYDTR VLCENGASPE EVADKVLNAV KRYQDVDSET FISTRHILPK
DCEQKVPTKF FSEAVTEGLA PDGGLFVPEK EFPKLNFGEW KSLVGATYIE RAQILLEKCI
HPADIPASRL GELIETAYGE NFACSKIAPV RHLSGNQFIL ELFHGPTGSF KDLSLQLMPH
LFAHCIPPSC NYMILVATSG DTGSAVLNGF SRLSKDDKQR IAVATFFPED GVSDFQKAQI
IGCQNENGWA VGVKSDFDFC QTSIKRIFQD SDFTGFLTVE YGTVLSSANS INWGRLLPQV
VYHASAYLDL VSQGFISFGS PVDVCIPTGN FGNILAAVYA KTMGIPIRKF ICASNQNHVL
TDFIKTGHYD LRERKLAQTF SPAIDILKSS NLERHLHLMA NKDGQLMTRL FNQLEEQHHF
QIEKILVEKI QQDFVADWCS EGECLAAIHS TYNTSGYILD PHTAVAKVVA DRMQDKTCPV
IVSSTAHYSK FAPAIMQALK IKEISQTSSS QVYLLSSYNA LPPPHEALLE RTKQQEKMEC
QVCAADVNVL KSHVEKLAQN HFI
//
