ID   A0A340WEG8_LIPVE        Unreviewed;       109 AA.
AC   A0A340WEG8;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Mitochondrial pyruvate carrier {ECO:0000256|RuleBase:RU363100};
GN   Name=MPC1 {ECO:0000313|RefSeq:XP_007445971.1,
GN   ECO:0000313|RefSeq:XP_007445972.1};
OS   Lipotes vexillifer (Yangtze river dolphin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Lipotidae; Lipotes.
OX   NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007445972.1};
RN   [1] {ECO:0000313|RefSeq:XP_007445971.1, ECO:0000313|RefSeq:XP_007445972.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- FUNCTION: Mediates the uptake of pyruvate into mitochondria.
CC       {ECO:0000256|RuleBase:RU363100}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC       inner membrane {ECO:0000256|ARBA:ARBA00004448,
CC       ECO:0000256|RuleBase:RU363100}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004448, ECO:0000256|RuleBase:RU363100}.
CC   -!- SIMILARITY: Belongs to the mitochondrial pyruvate carrier (MPC) (TC
CC       2.A.105) family. {ECO:0000256|ARBA:ARBA00006416,
CC       ECO:0000256|RuleBase:RU363100}.
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DR   RefSeq; XP_007445971.1; XM_007445909.1.
DR   RefSeq; XP_007445972.1; XM_007445910.1.
DR   STRING; 118797.A0A340WEG8; -.
DR   GeneID; 103078126; -.
DR   KEGG; lve:103078126; -.
DR   CTD; 51660; -.
DR   OrthoDB; 3375631at2759; -.
DR   Proteomes; UP000265300; Unplaced.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006850; P:mitochondrial pyruvate transmembrane transport; IEA:InterPro.
DR   InterPro; IPR005336; MPC.
DR   PANTHER; PTHR14154:SF8; MITOCHONDRIAL PYRUVATE CARRIER 1; 1.
DR   PANTHER; PTHR14154; UPF0041 BRAIN PROTEIN 44-RELATED; 1.
DR   Pfam; PF03650; MPC; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Mitochondrion {ECO:0000256|ARBA:ARBA00023128,
KW   ECO:0000256|RuleBase:RU363100};
KW   Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792,
KW   ECO:0000256|RuleBase:RU363100};
KW   Pyruvate {ECO:0000313|RefSeq:XP_007445971.1,
KW   ECO:0000313|RefSeq:XP_007445972.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265300};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363100}.
SQ   SEQUENCE   109 AA;  12362 MW;  F6F64D89FAA68124 CRC64;
     MAGALVRKAA DYVRSKDFRD YLMSTHFWGP VANWGLPIAA INDMKKSPEI ISGRMTFALC
     CYSLTFMRFA YKVQPRNWLL FACHATNEVA QLTQGGRLLR HEMSKNASA
//