ID A0A340WIX0_LIPVE Unreviewed; 406 AA.
AC A0A340WIX0;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Interferon regulatory factor 4-like {ECO:0000313|RefSeq:XP_007446960.1};
GN Name=LOC103089569 {ECO:0000313|RefSeq:XP_007446960.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007446960.1};
RN [1] {ECO:0000313|RefSeq:XP_007446960.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007446960.1; XM_007446898.1.
DR AlphaFoldDB; A0A340WIX0; -.
DR STRING; 118797.A0A340WIX0; -.
DR GeneID; 103089569; -.
DR KEGG; lve:103089569; -.
DR InParanoid; A0A340WIX0; -.
DR OrthoDB; 3740806at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:UniProt.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd00103; IRF; 1.
DR Gene3D; 2.60.200.10; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR019817; Interferon_reg_fac_CS.
DR InterPro; IPR001346; Interferon_reg_fact_DNA-bd_dom.
DR InterPro; IPR019471; Interferon_reg_factor-3.
DR InterPro; IPR017855; SMAD-like_dom_sf.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11949; INTERFERON REGULATORY FACTOR; 1.
DR PANTHER; PTHR11949:SF24; IRF TRYPTOPHAN PENTAD REPEAT DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00605; IRF; 1.
DR Pfam; PF10401; IRF-3; 1.
DR PRINTS; PR00267; INTFRNREGFCT.
DR SMART; SM00348; IRF; 1.
DR SMART; SM01243; IRF-3; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00601; IRF_1; 1.
DR PROSITE; PS51507; IRF_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265300}.
FT DOMAIN 7..115
FT /note="IRF tryptophan pentad repeat"
FT /evidence="ECO:0000259|PROSITE:PS51507"
FT REGION 138..200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..171
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 406 AA; 45566 MW; 567FC4249997ABB3 CRC64;
MAGAGGPLRL RDWLVAQIES GRYAGLRWED AGKTLFRIPW KHAAKQGYQA QQDAALFRAW
AIYKGKHLEG VDKEDPSTWK TRLRCALNKS ADFCEVRSLN QLDISNPYKV YRLLSDGAHS
PVTRACAPCK EEGILHSQQV HPGEVTEPAC KTEEQVGSRL VTEDKDKEQP PRLASLPPGP
LAGHRYQAQD PAHPWGPSPS EDFSNPDFWL HVRLFYGAEL VREATARAAE GCSLSPRAAA
AAAELLLGPP PRVAQVRFPE PPPGARVLRR LLSHLERGVL LWVAPEGVFA KRLCRGRVYW
RGPLAPHRAR PNKLERELTC QLLDTRRFLA ELRAHLHDGH REPEYQIRLC FGEEYPGPPD
QPEERLIMAH VEPVFARELL LHSKLHGQVP RWRVPSPASP TASLTC
//
