ID A0A340WL06_LIPVE Unreviewed; 1034 AA.
AC A0A340WL06;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=FERM domain-containing protein 4B {ECO:0000313|RefSeq:XP_007447710.1};
GN Name=FRMD4B {ECO:0000313|RefSeq:XP_007447710.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007447710.1};
RN [1] {ECO:0000313|RefSeq:XP_007447710.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_007447710.1; XM_007447648.1.
DR AlphaFoldDB; A0A340WL06; -.
DR STRING; 118797.A0A340WL06; -.
DR GeneID; 103073820; -.
DR KEGG; lve:103073820; -.
DR CTD; 23150; -.
DR InParanoid; A0A340WL06; -.
DR OrthoDB; 3400049at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0090162; P:establishment of epithelial cell polarity; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13191; FERM_C_FRMD4A_FRMD4B; 1.
DR CDD; cd17200; FERM_F1_FRMD4B; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR021774; CUPID.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR047176; FRMD4A/B.
DR InterPro; IPR041785; FRMD4A/B_FERM_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR46079; FERM DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR46079:SF1; FERM DOMAIN-CONTAINING PROTEIN 4B; 1.
DR Pfam; PF11819; CUPID; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PRINTS; PR00935; BAND41.
DR SMART; SM00295; B41; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265300}.
FT DOMAIN 59..361
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 577..615
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 634..699
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 711..736
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 754..788
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 905..956
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 993..1034
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 579..610
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 634..653
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 664..699
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 715..736
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 770..788
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 908..926
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 939..956
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 998..1016
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1034 AA; 117650 MW; B93CC0FB13ED7BC1 CRC64;
MASVFMCGVE DLLFSGSRFV WNLTVSTLRR WYTQRLRACH QVLRTWCGLR DVYQMTEGRH
CQVHLLDDRR LELLVQPKLL SRELLDLVAS HFNLKEKEYF GITFTDDTGQ QNWLQLDHRV
LDHDLPKKPG PTVLYFSVRF YIESISFLKD KTTVELFFLN AKACVHKGQI EVDSETIFRL
AALILQEAKG DYTSHENARK DLKTLPAFPT KTLQEHPSLA YCEDRVIEHY LKIKGLTRGQ
AVVQYMKIVE ALPTYGVHYY AVKDKQGLPW WLGISYKGIG QYDLQDKVKP RQLFQWKQLE
NLYFREKKFA VEVHDPRRIS VSRRTFGQSG LFVQTWYANS SLIKSIWVMA ISQHQFYLDR
KQSKAKIPSA RSLDDIAMDL TETGTPRVSK MVTLEAKSQF IMASNGSLIS SGSQDSEVSE
EQKREKILEL KKKEKLLQEK LLKKVEELKK ICLREAELTG KMPKEYPLNI GEKPPHVRRR
VGTAFKLDDN LLPSEEDPAL QELESNFLIQ QKLVEAAKKL ANEPDLCKTV KKKRKQDYTD
AVKKLQEIEN AINEYRIRCG KKPSQKATVI LPEDIIPSEG SSLSDTTTYD DSSDTCTLAG
QQSSSVPHSP RILPPKSLGI ERIHFRKSSI NEQFVDTRQS REMLSTHSSP YKTLERRPQG
GRSVPTTPVL TRNAYSSSHL QPESSSQHCR QRSGSLESQS HLLSEMDHDK PFLSLSKSQR
SSSTEILDDG SSYTSQSSTE YYCVTPVAGP CYTTQTLDTR SRGRRRSKKQ NVSTSNSGSM
PNLAQKDSLK NGVYSKSQEQ PSSYYTAGYT PYAECDLYYS GGYVYENDTE GQYSVNPSYR
SSAHYGYDHP RDYSRSFHED EVDRVPHNPY ATLRLPRKAA AKSEHITKNI HKALVAEHLR
GWYQRASGQK EQGHSTQSSF DSDRGSQRSL GFAGLQVPCS PSSRASSYSS VSSTNASGNW
RTQITIGLSE YETPAHSSYT SCYGNVYNPL PSPGRPYTET GQLDNTEGNP LEDSLENSEQ
RLFWHEDSKP GTLV
//
