ID A0A340WL64_LIPVE Unreviewed; 929 AA.
AC A0A340WL64;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Exocyst complex component 2 {ECO:0000256|ARBA:ARBA00017526, ECO:0000256|RuleBase:RU365069};
GN Name=EXOC2 {ECO:0000313|RefSeq:XP_007448367.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007448367.1};
RN [1] {ECO:0000313|RefSeq:XP_007448367.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Component of the exocyst complex involved in the docking of
CC exocytic vesicles with fusion sites on the plasma membrane.
CC {ECO:0000256|ARBA:ARBA00002660, ECO:0000256|RuleBase:RU365069}.
CC -!- SUBUNIT: Component of the exocyst complex.
CC {ECO:0000256|RuleBase:RU365069}.
CC -!- SIMILARITY: Belongs to the SEC5 family. {ECO:0000256|ARBA:ARBA00010578,
CC ECO:0000256|RuleBase:RU365069}.
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DR RefSeq; XP_007448367.1; XM_007448305.1.
DR AlphaFoldDB; A0A340WL64; -.
DR STRING; 118797.A0A340WL64; -.
DR GeneID; 103070242; -.
DR KEGG; lve:103070242; -.
DR CTD; 55770; -.
DR InParanoid; A0A340WL64; -.
DR OrthoDB; 2901642at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0000145; C:exocyst; IEA:UniProtKB-UniRule.
DR GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR GO; GO:0006893; P:Golgi to plasma membrane transport; IEA:UniProtKB-UniRule.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd00603; IPT_PCSR; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR029175; EXOC2/Sec5.
DR InterPro; IPR039481; EXOC2/Sec5_N_dom.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR PANTHER; PTHR13043:SF1; EXOCYST COMPLEX COMPONENT 2; 1.
DR PANTHER; PTHR13043; EXOCYST COMPLEX COMPONENT SEC5; 1.
DR Pfam; PF15469; Sec5; 1.
DR Pfam; PF01833; TIG; 1.
DR SUPFAM; SSF81296; E set domains; 1.
PE 3: Inferred from homology;
KW Exocytosis {ECO:0000256|ARBA:ARBA00022483, ECO:0000256|RuleBase:RU365069};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|RuleBase:RU365069};
KW Reference proteome {ECO:0000313|Proteomes:UP000265300};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365069}.
FT DOMAIN 8..91
FT /note="IPT/TIG"
FT /evidence="ECO:0000259|Pfam:PF01833"
FT DOMAIN 133..914
FT /note="Exocyst complex component EXOC2/Sec5 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF15469"
SQ SEQUENCE 929 AA; 104071 MW; 99D01020D9CE6FE2 CRC64;
MSRTRQPPLV TGISPNEGIP WTKVTIRGEN LGTGPADLIG LTICGHNCLL TAEWMSPSKI
VCRVGQAKND KGDIIVTTKS GGKGTSTVSF KLLRPEKIGI LDQSAVWVDE MNYYDMRTDR
NKGIPPLSLR PANPLGIEIE KGKFPQKDLE MLFPGMSADF TSENFSAAWY LIENHSNTSF
EQLKMAVTHL KRQANKKSEG SLACVKGGLS TFFEAQDALS AIHQKLEADG TEKVEGSMTQ
KLENVLNRAS NTADTLFQEV LGRKDKADST RNALNVLQRF KFLFNLPLSI ERNIQKGDYD
VVINDYEKAK SLFGKTEVQV FKKYYAEVET RIEALRELLL DKLLETPSTL HDQKRYIRYL
SDLHAPGDPA WQCIGAQHRW ILQLMHSCQE GCVRDLKGPP GLHSATLDLD GDVRASVPGH
LGQTASLKRG SSFQPGRDDA WRYQTPHRVA FVEKLTKLVL SQLPNFWKLW ISYVNGSLFS
ETAEKSGHIE RSKNVRQRQN DFKKMIQEVM HCLVKLLRGA LLPLGVTEGG GRQCRGWEVK
AELSGQGLAH AIQTLRLTYE SLTALEIPND LLQTIQDLVL DLRVRCVVVT LQHTAEEVKR
LAEKEDWVVD SEGLTSLPCH FERCVVHSLQ SLREVLECKP GEASVFQQPK TQEEVCQLSI
NIMQVFIYCL EQLSTKPDAD VDTAHLSVDV SSPDLFGSIH EDFSLTSEQR LLIVLSNCCY
LERHTFRNIA EHFEKHNFQG IEKITQVSMA SLKELDQRLF ENYIELKADP IVGSLEPGIY
AGYFDWKDCL PPTGVRNYLK EALVNIIAVH AEVFTISKDL VPRVLSRVVE AVSEELCRLM
QCVSSFSKNG ALQARLEICT LRDTVAAHLT PESRSSFKQA LEALPQLSSG ADRKLLELLL
SRVRSGVHLQ LACFQATPPP AVKTQVPSR
//
