ID A0A340WMT1_LIPVE Unreviewed; 371 AA.
AC A0A340WMT1;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Partitioning defective 6 homolog gamma {ECO:0000313|RefSeq:XP_007450016.1};
GN Name=PARD6G {ECO:0000313|RefSeq:XP_007450016.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007450016.1};
RN [1] {ECO:0000313|RefSeq:XP_007450016.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell junction, tight junction
CC {ECO:0000256|ARBA:ARBA00004435}. Cytoplasm
CC {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the PAR6 family.
CC {ECO:0000256|ARBA:ARBA00008625}.
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DR RefSeq; XP_007450016.1; XM_007449954.1.
DR AlphaFoldDB; A0A340WMT1; -.
DR STRING; 118797.A0A340WMT1; -.
DR GeneID; 103079367; -.
DR KEGG; lve:103079367; -.
DR CTD; 84552; -.
DR InParanoid; A0A340WMT1; -.
DR OrthoDB; 5401122at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd06403; PB1_Par6; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR InterPro; IPR000270; PB1_dom.
DR InterPro; IPR034868; PB1_Par6.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR14102; PAR-6-RELATED; 1.
DR PANTHER; PTHR14102:SF3; PARTITIONING DEFECTIVE 6 HOMOLOG GAMMA; 1.
DR Pfam; PF00564; PB1; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00666; PB1; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS51745; PB1; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Membrane {ECO:0000256|ARBA:ARBA00022475};
KW Reference proteome {ECO:0000313|Proteomes:UP000265300};
KW Tight junction {ECO:0000256|ARBA:ARBA00022427}.
FT DOMAIN 18..98
FT /note="PB1"
FT /evidence="ECO:0000259|PROSITE:PS51745"
FT DOMAIN 157..250
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 258..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 350..371
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..279
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 371 AA; 40802 MW; 219E7E308C486F54 CRC64;
MNRSFHKSQT LRFYDCSAVE VKSKFGAEFR RFSLDRQKPG KFEDFYKLVV HTHHISNTEV
TIGYADVHGD LLPINNDDNF CKAVSSANPL LRVFIQKREE AERCSFGVGS LSRRRRPLAL
REDGPRRRTH LHIGLPHDFR PVSSIIDVDI LPETHRRVRL YRHGCQKPLG FYIRDGTSVR
VAPQGLEKVP GIFISRMVPG GLAESTGLLA VDDEVLEVNG IEVAGKTLDQ VTDMMIANSH
NLIVTVKPAN QRNNVVRGSR ALGSSGRSLD STASRHSLPA AHVLQNLPPD EMESDEEADV
VLEGVLEPRL VPRPPPGSLA RVNGAGLAPG LHSPGREGSV QRLLSSLRSD PRHSLALPPG
GVEEHGPAVT L
//
