ID A0A340WNH7_LIPVE Unreviewed; 696 AA.
AC A0A340WNH7;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Solute carrier family 53 member 1 {ECO:0000256|ARBA:ARBA00035271};
DE AltName: Full=Phosphate exporter SLC53A1 {ECO:0000256|ARBA:ARBA00035512};
GN Name=XPR1 {ECO:0000313|RefSeq:XP_007448575.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007448575.1};
RN [1] {ECO:0000313|RefSeq:XP_007448575.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=phosphate(in) = phosphate(out); Xref=Rhea:RHEA:32823,
CC ChEBI:CHEBI:43474; Evidence={ECO:0000256|ARBA:ARBA00035090};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:32824;
CC Evidence={ECO:0000256|ARBA:ARBA00035090};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SYG1 (TC 2.A.94) family.
CC {ECO:0000256|ARBA:ARBA00009665}.
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DR RefSeq; XP_007448575.1; XM_007448513.1.
DR AlphaFoldDB; A0A340WNH7; -.
DR STRING; 118797.A0A340WNH7; -.
DR GeneID; 103072079; -.
DR KEGG; lve:103072079; -.
DR CTD; 9213; -.
DR InParanoid; A0A340WNH7; -.
DR OrthoDB; 7162at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd14477; SPX_XPR1_like; 1.
DR InterPro; IPR004342; EXS_C.
DR InterPro; IPR004331; SPX_dom.
DR PANTHER; PTHR10783:SF103; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1; 1.
DR PANTHER; PTHR10783; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED; 1.
DR Pfam; PF03124; EXS; 1.
DR Pfam; PF03105; SPX; 3.
DR PROSITE; PS51380; EXS; 1.
DR PROSITE; PS51382; SPX; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_007448575.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000265300};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 237..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 474..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 508..527
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..177
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT DOMAIN 439..643
FT /note="EXS"
FT /evidence="ECO:0000259|PROSITE:PS51380"
FT COILED 70..97
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 696 AA; 81532 MW; 455243C03EFC9C66 CRC64;
MKFAEHLSAH ITPEWRKQYI QYEAFKDMLY SAQDQAPSVE VTDEDTVKRY FAKFEEKFFQ
TCEKELAKIN TFYSEKLAEA QRRFATLQNE LQSSLDAQKE STGVTTLRQR RKPVFHLSHE
ERVQHRNLKD LKLAFSEFYL SLILLQNYQN LNFTGFRKIL KKHDKILETS RGADWRVAHV
EVAPFYTCKK INQLISETEA VVTNELEDGD RQKAMKRLRV PPLGAAQPAP AWTTFRVGLF
CGIFIVLNIT LVLAAVFKLE TDRSIWPLIR IYRGGFLLIE FLFLLGINTY GWRQAGVNHV
LIFELNPRSN LSHQHLFEIA GFLGILWCLS LLACFFAPVS VIPTYVYPLV LYGFMVFFLI
NPTKTFYYKS RFWLLKLLFR VFTAPFHKVG FADFWLADQL NSLSVILMDL EYMICFYSFE
LKWDESGGLL PNDSEEPEIC HNYSYGVRAI VQCIPAWLRF IQCLRRYRDT KRAFPHLVNA
GKYSTTFFTV TFAALYSTHK ERGHSDTIVF FYLWIVFCII SSCYTLIWDL KMDWGLFDKN
AGENTFLREE IVYPQKAYYY CAIIEDVILR FAWTIQISIT SMTLLPHSRD IIATVFAPLE
VFRRFVWNFF RLENEHLNNC GEFRAVRDIS VAPLNADDQT LLEQMMDQED GVRNRQKNRP
WKYSQSISLR RPCLASQSKA RDTKVLIEDT DDEANT
//
