ID A0A340WPF0_LIPVE Unreviewed; 830 AA.
AC A0A340WPF0;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Stromal interaction molecule 2 isoform X2 {ECO:0000313|RefSeq:XP_007448875.1};
GN Name=STIM2 {ECO:0000313|RefSeq:XP_007448875.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007448875.1};
RN [1] {ECO:0000313|RefSeq:XP_007448875.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR RefSeq; XP_007448875.1; XM_007448813.1.
DR AlphaFoldDB; A0A340WPF0; -.
DR GeneID; 103078894; -.
DR CTD; 57620; -.
DR OrthoDB; 54068at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005246; F:calcium channel regulator activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.
DR GO; GO:0006874; P:intracellular calcium ion homeostasis; IEA:InterPro.
DR GO; GO:0051049; P:regulation of transport; IEA:UniProt.
DR CDD; cd09574; SAM_STIM2; 1.
DR CDD; cd11722; SOAR; 1.
DR Gene3D; 1.10.238.180; -; 1.
DR Gene3D; 1.10.287.3550; -; 1.
DR Gene3D; 1.20.5.340; -; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR032393; SOAR.
DR InterPro; IPR037608; STIM.
DR InterPro; IPR037610; STIM2_SAM.
DR PANTHER; PTHR15136:SF2; STROMAL INTERACTION MOLECULE 2; 1.
DR PANTHER; PTHR15136; STROMAL INTERACTION MOLECULE HOMOLOG; 1.
DR Pfam; PF07647; SAM_2; 1.
DR Pfam; PF16533; SOAR; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Calcium transport {ECO:0000256|ARBA:ARBA00022568};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000265300};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 221..279
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 601..646
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 677..697
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 709..731
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 774..830
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 337..374
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 16..41
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..70
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 601..615
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 678..697
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 774..790
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 830 AA; 92783 MW; 678FD4B907AB25B6 CRC64;
MNAAGTRAPE AAGADGTRLE PDRSSRLRRR GRPEESQEAA APREAGEWLA AGAPPRFPSA
PPPRPHPATT PGPASGWLRR RRWAALLVLG LLVAGAADGC ELVPRHLRGR RTAGSAAAAA
SSPAAAGGDS PALMTDPCMS LSPPCFTEED RFSLEALQTI HKQMDDDKDG GIEVDESDEF
IREDMKYKDA TNKHSHLHRE DKHITVEDLW KRWKTSEVHN WTLEDTLQWL IEFVELPQYE
KNFRDNNVKG TTLPRIAVHE PSFMISQLKI SDRSHRQKLQ LKALDVVLFG PLTRPPHNWM
KDFILTVSIV IGVGGCWFAY TQNRTSKEHV AKMMKDLESL QTAEQSLMDL QERLEKAQEE
NRNVAVEKQN LERKMMDEIN YAKEEACRLR ELREGAECEL SRRQYAEQEL EQVRMALKKA
EKEFELRSSW SVPDALQKWL QLTHEVEVQY YNIKRQNAEM QLAIAKDEAE KIKKKRSTVF
GTLHVAHSSS LDEVDHKILE AKKALSELTT CLRERLFRWQ QIEKICGFQI AHNSGLPSLT
SSLYSDHSWV VMPRVSIPPY PIAGGVDDLD EDTPPIVSQF PGTMAKPAGS LARSSSLCRS
RRSIVPSSPQ SQRAQLPAHA HPAHPRHPHH PQHTQHSLPS PDPDILSVSS CPALYRNEEE
EEAIYFSAEK QWEVPDTASE CDSLNSSIGR KQSPPSSLEI YQTLSPRKIS RDELSLEDSS
RGESPIAADI SRGSPNCVGL TETKSMIFSP ASKVYNGILE KSCSMNQLSS GIPVPKPRHT
SCSSAGNDSK PVQEAPGVAR ISSIPHDLCH NGEKSKKPSK IKSLFKKKSK
//
