ID A0A340WRB0_LIPVE Unreviewed; 544 AA.
AC A0A340WRB0;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Homeobox and leucine zipper protein Homez isoform X2 {ECO:0000313|RefSeq:XP_007449614.1};
GN Name=HOMEZ {ECO:0000313|RefSeq:XP_007449614.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007449614.1};
RN [1] {ECO:0000313|RefSeq:XP_007449614.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108}.
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DR RefSeq; XP_007449614.1; XM_007449552.1.
DR AlphaFoldDB; A0A340WRB0; -.
DR GeneID; 103087796; -.
DR CTD; 57594; -.
DR OrthoDB; 4218493at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd00086; homeodomain; 2.
DR Gene3D; 1.10.10.60; Homeodomain-like; 3.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR024578; Homez_homeobox_dom.
DR PANTHER; PTHR15467:SF7; HOMEOBOX AND LEUCINE ZIPPER PROTEIN HOMEZ; 1.
DR PANTHER; PTHR15467; ZINC-FINGERS AND HOMEOBOXES RELATED; 1.
DR Pfam; PF11569; Homez; 1.
DR SMART; SM00389; HOX; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000313|RefSeq:XP_007449614.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000265300}.
FT DOMAIN 350..410
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 352..411
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 179..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 423..461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 508..544
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 210..229
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 268..288
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..461
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 544 AA; 60722 MW; CFA7C4DC5B082EA8 CRC64;
MVRGWEPPPG PDCAISEGHK SESTMPPNKE ASGLNSSPAG LICLPPISEE LQLVWTQAAQ
TSELDGNEHL LQTFSYFPYP SLADIALLCL RYGLQMEKVK TWFMAQRLRC GISWSSEEIE
ETRARVVYHR DQLHFKSLLS FTHHAGRPPE EVPPSPVPPP EQVGLGIVPL TLSEPTQMKG
LKVEPSEPSE PLSHQKAKEP LMAPGSGVFP HQSQFWQDLQ SSGLSKEQAG KGPDQSHGLG
TASWNHSTAV HQPRARDKPP PVSLLASSCK KESASNVTPP SSTSSSSFQV LANGATATSK
PLQPLGCVPQ PLSPNEQALR PQLEPAWPQG LRHNSAPGRV GPAEYLSPDM QRQRKTKRKT
KEQLAILKSF FLQCQWARRE DYHKLEQITG LPRPEIIQWF GDTRYALKHG QLKWFRDNAV
PGAPSFQDPA IPTPPPSTRS LNEWAETPPL PIPPPPPDIR PLERYWATHQ QLRESDIPQL
SQASRLSTQQ VLDWFDSRLP EPAEVVVCLD EEEEEEEEEL PEDDEDEEEE EEDDDDDDDV
IIQD
//
