ID A0A340WT96_LIPVE Unreviewed; 640 AA.
AC A0A340WT96;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=RNA polymerase II elongation factor ELL2 {ECO:0000313|RefSeq:XP_007450294.1};
GN Name=ELL2 {ECO:0000313|RefSeq:XP_007450294.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007450294.1};
RN [1] {ECO:0000313|RefSeq:XP_007450294.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ELL/occludin family.
CC {ECO:0000256|ARBA:ARBA00009171, ECO:0000256|PROSITE-ProRule:PRU01324}.
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DR RefSeq; XP_007450294.1; XM_007450232.1.
DR AlphaFoldDB; A0A340WT96; -.
DR STRING; 118797.A0A340WT96; -.
DR GeneID; 103075138; -.
DR KEGG; lve:103075138; -.
DR CTD; 22936; -.
DR InParanoid; A0A340WT96; -.
DR OrthoDB; 2910197at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0008023; C:transcription elongation factor complex; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006368; P:transcription elongation by RNA polymerase II; IEA:InterPro.
DR Gene3D; 6.10.140.340; -; 1.
DR Gene3D; 1.10.10.2670; E3 ubiquitin-protein ligase; 1.
DR InterPro; IPR042065; E3_ELL-like.
DR InterPro; IPR031176; ELL/occludin.
DR InterPro; IPR019464; ELL_N.
DR InterPro; IPR010844; Occludin_ELL.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR23288; OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL; 1.
DR PANTHER; PTHR23288:SF8; RNA POLYMERASE II ELONGATION FACTOR ELL2; 1.
DR Pfam; PF10390; ELL; 1.
DR Pfam; PF07303; Occludin_ELL; 1.
DR SUPFAM; SSF144292; occludin/ELL-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51980; OCEL; 1.
PE 3: Inferred from homology;
KW Elongation factor {ECO:0000313|RefSeq:XP_007450294.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein biosynthesis {ECO:0000313|RefSeq:XP_007450294.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000265300};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 526..636
FT /note="OCEL"
FT /evidence="ECO:0000259|PROSITE:PS51980"
FT REGION 172..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 290..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 338..478
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 497..517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 184..204
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..317
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 342..356
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..384
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 385..438
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 499..517
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 640 AA; 72151 MW; 8F3A721D7E90C288 CRC64;
MAAGGAAGLR EEQRYGLSCG RLGQDNTTVL HVKLTETAIR ALETYQSHEN LIPFRPSIQF
QGLQGLVKIP KNDPPNEVHT FNFYLSNVGK DNPQGSFDCI QQTFSSSGAS QLNCLGFIQD
KITVCATNDS YQMTRERMTQ AEEESRNRST KVIKPGGPYV GKRVQIRKAP QAVSDAVPER
KRSTPMNPAN TIRKTHSSSS VSQRPYRDRV IHLLALKAYK KPELLARLQK DGVNQKDKNS
LGAILQQVAN LNPKDLSYTL KDYVFKELQR DWPGYNEIDR RSLESVLSRK LNPSQNAAST
SRSESPVCSS RDAASSPQKR LLDSDFIDPL MNKKARISHL TNRVPPTLNG HLNPTSEKSA
AGPPLPPAAA AIPTPPPLPS THLPVSNPPQ TVNSHSNSPS TPEGRGTQDL PVDSFSQNGS
ICEDQQDKYT SRTSLETLPP GSVLLKCPKP MEENHSSHKK SKKKSKRHKE KDQIKKHDIE
MIEEKEEDLK REEEIAKLNN SSPDSNEGVK EDCTASTEAS STIELPDYLI KYIAIVSYEQ
RQNYKDDFNA EYDEYRALHA RMETVARRFI KLDAQRKRLS PGSKEYQSVH EEVLQEYQKI
KQSSPNYHEE KYRCEYLHNK LAHIKRLIGE FDQQQAESWH
//
