ID A0A340WWG5_LIPVE Unreviewed; 319 AA.
AC A0A340WWG5;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Homeobox protein PKNOX1 isoform X2 {ECO:0000313|RefSeq:XP_007451190.1};
GN Name=PKNOX1 {ECO:0000313|RefSeq:XP_007451190.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007451190.1};
RN [1] {ECO:0000313|RefSeq:XP_007451190.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
CC -!- SIMILARITY: Belongs to the TALE/MEIS homeobox family.
CC {ECO:0000256|ARBA:ARBA00009661}.
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DR RefSeq; XP_007451190.1; XM_007451128.1.
DR AlphaFoldDB; A0A340WWG5; -.
DR GeneID; 103082286; -.
DR CTD; 5316; -.
DR OrthoDB; 3180467at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR InterPro; IPR032453; PKNOX/Meis_N.
DR PANTHER; PTHR11850:SF80; HOMEOBOX PROTEIN PKNOX1; 1.
DR PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR Pfam; PF16493; Meis_PKNOX_N; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000313|RefSeq:XP_007451190.1};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000265300}.
FT DOMAIN 140..203
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 142..204
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 284..319
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 319 AA; 34220 MW; FD699288F4C95459 CRC64;
MVKAIQVLRI HLLELEKVNE LCKDFCSRYI ACLKTKMNSE TLLSGEPGSP YSPVQSQQIQ
SAITGTLSPQ GIVVPASALQ QGNVTMATVA GGTVYQPVTV VTPQGQVVTQ ALSPGTIRIQ
NSQLQLQLNQ DLSILHQDDG SSKNKRGVLP KHATNVMRSW LFQHIGHPYP TEDEKKQIAA
QTNLTLLQVN NWFINARRRI LQPMLDSSCS ETPKTKKKTA QNRPVQRFWP DSIASGAAQP
ATSELTVSEG AVVTITAPVG MNVDSLQSLS SDGATLAVQQ VMMAEQSEDD SVDSTGDGGA
ALAPGHLGGL VLENSDSLQ
//
