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Database: UniProt
Entry: A0A340WWX7_LIPVE
LinkDB: A0A340WWX7_LIPVE
Original site: A0A340WWX7_LIPVE 
ID   A0A340WWX7_LIPVE        Unreviewed;      3071 AA.
AC   A0A340WWX7;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   10-FEB-2021, entry version 12.
DE   SubName: Full=centromere protein F {ECO:0000313|RefSeq:XP_007451350.1};
GN   Name=CENPF {ECO:0000313|RefSeq:XP_007451350.1};
OS   Lipotes vexillifer (Yangtze river dolphin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Lipotidae; Lipotes.
OX   NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007451350.1};
RN   [1] {ECO:0000313|RefSeq:XP_007451350.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (OCT-2020) to UniProtKB.
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DR   RefSeq; XP_007451350.1; XM_007451288.1.
DR   GeneID; 103089851; -.
DR   KEGG; lve:103089851; -.
DR   CTD; 1063; -.
DR   Proteomes; UP000265300; Genome assembly.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 2.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 2.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265300}.
FT   DOMAIN          1..304
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          2088..2227
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2270..2409
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2926..2970
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          188..233
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          457..489
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          766..786
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          802..825
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1360..1383
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1660..1684
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2846..3071
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          13..131
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          273..381
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          506..703
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          715..756
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          836..870
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          896..954
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          966..986
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1033..1053
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1086..1106
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1115..1149
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1200..1227
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1281..1315
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1542..1562
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1574..1612
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1783..1845
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1879..1899
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1907..1934
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1949..2042
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2064..2091
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2099..2154
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2162..2242
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2281..2308
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2313..2424
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2432..2452
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2460..2560
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2586..2634
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2646..2782
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2793..2820
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        192..233
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        472..489
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1366..1383
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1664..1684
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2846..2889
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2908..2928
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2956..2970
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2986..3037
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   3071 AA;  352236 MW;  773D9F8E448504E4 CRC64;
     MSWALEEWKE GLPTRALQKI QELEGQLDKL KKERQQRQFQ LETLEAALQK QKQKVENEKA
     EGANLKRENQ SLMEICENLE KTKQKISHEL QVKESQVNFQ EGQLNSSKKQ IEKLEQELKR
     CKSELERSQQ AAQSADVSMS PCTTPQKIFA TPLTPSQYYS GSKYEDLKEK YNKEVEERKR
     LEAEVKALQA KKASQATPQS TMNHRDIARH QASSSVFSWQ QEKTPSRLSS SALKTPVRRD
     FSASNFSGEQ EVTLSRSTLQ IGNRDANSSF CDNSNLLDQL KAQNQELRSK ISELELRLQG
     QEREMKGQVN KLQELQLQVE KAKVELNEKE KVLNKSRDEL VRTTAQYDQA STKCLALEQK
     LKKLTEDLSC QRQNAESARC SLEQKIKEKE KEFQEELSRQ QHSFQTLDQE FTQMKAKLTQ
     ELQQAKNMHN ILQAELDKVT SVKHQLEKKL EEFKEKFSRT EQTLQASQTK ENELRRSSEE
     MKRENSLLKS QSEQRARAVC YLEEELKKAK QRLSQSQNFA EEMRAKNTSQ ETMLRDLQEK
     INQQENSLTL EKLKLALADL EKQRDCSQDL LKKREHHIEQ LNEKLSKTER ESEALLSALE
     LKKKEYEELK EEKALFSRWK SENEQLLNQM ESEKESLQSK INHLETCLKT QQIKSHEYNE
     RVRTLEMERE NLNVEIRNLH NVIDSKTAEA ETQKQAYGEL QQKAEFSDQK HEKEIENMCL
     KISQLTGQVE DLEDKLQSLS SEIMDKNQRY QDLHAESESL RDLLKSRDSS AVTNESHQRS
     LLASEQQSAV NNSFANIIEE QESVPSERSE CHLETDQSPK SSSMLQNRVV SLEFSLESQK
     QMNSDLQKQC EELVQIKGEI EENLMKAEQM HQSFVAETSQ RISKLQEDTS VHQNVVVETL
     VTLESKEREL QLLNEKLETE QAEIQELKKS NHLLQESLKE LQLLSETLSL EKKEMSSIIS
     LDKKDIEELT QENGTLKEIN AALTQEKMNL LRKTESFSNC IDERDKSISE LSDQYKQERL
     TWLQRCEETG NAFRDLSEKY KAEQEKNSKL ECLLNECTSV CEDRKTELGQ LKETFAREHQ
     AFVSQLALAE ERNQSLILEL ETVQQALRSE VTDIQSNSKR EADGLKQEIM TLKEEQSKMQ
     QEVNALLQEK EHLVELMTTR HEHQHLELEP IQDSVKVAQR KINTRHVQLP TDLEVKDASL
     DSYSAQLAQV ESKVRNMELK LQESEGEEYL EHGLQIGELE AGDVQQDTQP RDISGLGNFE
     IDPEERYISV LHELSTSQQD NAHLQCSLQT AMNKLDELEK MCEVLQVEKL ELISELNDSR
     SECVTAASRM AEEVGKLVNE VKILDDEHGL LQGKCVKETP ESEFGEQQDE QTSVSLNPLD
     DSNSHEHLTV SNKEVHMHFA ELQEKFSSLQ SEHKILHDQH CQMSSKMSEL QSYIDTLKAE
     NSVLSTSLRN SQGDLVKEVM PGPGEKHFLS LSLSGVTDSP GNAIEASFYK DLLEHMRETS
     LLNNLDRTVL AHQSSVEEVS CGSLEGENLT EKEIPSAPVR SVEELETVCQ MYLQSFKKLE
     EKIESQGITK NKEIEELERL LSSSREELDC LRKQYLSENE QWQQKLTSVT AEMESKLAAE
     KKHTEHLTLE LEVARLQLQG LDLSSRSLLG TDIEDAVRGG NNSCDIRESE DYTSETKERT
     PKHEIHQICE KDQDLSLEME KITKTSAIKL IGEWSREQSP ETSPRTPVED TTQGCSECIS
     ELSLSGPNAS VPMDFLENQV TIQNLQLQVK ETSNENLRLL HGIKERDQKV ESLLNEIKEL
     DSKLSLQEVQ LTTKIEACIE LEKVVEELQK EKSDFSEKLE SFSRDNQRVE SSGGLTSNLE
     MGTDKLSHEG IEDEVAKVTD NWRERCLNVE NELQRMKAER GSTEHHALSA EANLEAVQTE
     KLFLEKDNEN KQKVITCLEE GLLVVTSERD QLRGELDTLS KENQELDQMS EKMKEKIREL
     ESHQDERLHL QEQLQSLEKD SQALSLVRSE LENQIRQLNK ETKSLVRESE SLQTKLSELE
     HEKLTVAKAL EAALMEKGEV AVRLSSTQEE VHQLRKGIEK LRVRIEADEK KQLHISEKLK
     ESERRNDSLQ DKVETLEREL HMAEENQELV ILDAENSKAE VETLRTQMEL MTESLKTLDL
     DLVTIRSEKE NLVKQLQEKQ GQVSELHTLL SSLKNVLEEK EREKIQMKEE SKAEVEILQT
     QLKELSEEVA ALCDDRETWE AEEQSPDSPV QEVHQLRNNI GKLKVHLDTD ERKQLHILAK
     LKESGHQAAL LKDTVENLER ELEVSGKNQA HVILEAEKSK AEVETLKAKI EETAANLRAL
     ELDLVNTRSE KEDLTKELQK EQGRVSELET LNSSYENLLQ EKEQEKEQMK EESKAVVEIL
     QTRLKELSEE VAALCDEQET WKAEEQSLSS QVDSLEHEKA QLLQGLDEAK SNYMLLQSSV
     NGLIQEVEDG KQKLEKKDEE IRILKNHIQD QEQLVSKLSQ MEGEQQLWEE QRTKLENLMV
     ELEQKTQVLQ SKNDTLQDTL EALQNSSKDL EKELELTKME KLSFVEKVNT MTVKETELQK
     EMLAMVQKTT ELKEEFSREK NRLTEDLKLV SEEIKSRKGQ LKELMLENSE LEKTLDCAHR
     GQMEKRGKMR EEIAEYQLRL QEAEKKHQAL LLDINKQYEM EIQTYREKLT SKEECLSSQK
     VEIDLLKSSK EELNNSLKVT TEILEELKKT KMENLKYADK LKKENDRAQG KIKLLIKSCK
     QLEEEKEMLQ KEVSHLEAAH EKQKAGTVVD ANVDELMTEM KELKETLEEK TKEADEYLDK
     YCSLLISHEK LEKAKEMLET QVARLSSQQS KVNLRSSPSL NSVVPGPSPV PSATEKKLSS
     GQNKASGKRQ RSGGIREDGG ETTPSTPEKF SKKSRKAGKS GIHPAEDAED AEPEPEGLPE
     VVKKGFADIP TGKTTPYILR RTTMVTRTSP RLAAQKLAPS PLSLDKENLA ETSKPTAGGS
     RSQKVKVTQQ SPVDSGTALR EPTTRSLSIS NLPERSSADS PREGLRAKQG RLAPSPEAGP
     ESKGSENCRV Q
//
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