ID A0A340WWX7_LIPVE Unreviewed; 3071 AA.
AC A0A340WWX7;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 10-FEB-2021, entry version 12.
DE SubName: Full=centromere protein F {ECO:0000313|RefSeq:XP_007451350.1};
GN Name=CENPF {ECO:0000313|RefSeq:XP_007451350.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007451350.1};
RN [1] {ECO:0000313|RefSeq:XP_007451350.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (OCT-2020) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_007451350.1; XM_007451288.1.
DR GeneID; 103089851; -.
DR KEGG; lve:103089851; -.
DR CTD; 1063; -.
DR Proteomes; UP000265300; Genome assembly.
DR GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 2.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 2.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000265300}.
FT DOMAIN 1..304
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 2088..2227
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2270..2409
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2926..2970
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 188..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 457..489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 766..786
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 802..825
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1360..1383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1660..1684
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2846..3071
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 13..131
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 273..381
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 506..703
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 715..756
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 836..870
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 896..954
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 966..986
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1033..1053
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1086..1106
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1115..1149
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1200..1227
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1281..1315
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1542..1562
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1574..1612
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1783..1845
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1879..1899
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1907..1934
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1949..2042
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2064..2091
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2099..2154
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2162..2242
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2281..2308
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2313..2424
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2432..2452
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2460..2560
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2586..2634
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2646..2782
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2793..2820
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 192..233
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 472..489
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1366..1383
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1664..1684
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2846..2889
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2908..2928
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2956..2970
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2986..3037
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3071 AA; 352236 MW; 773D9F8E448504E4 CRC64;
MSWALEEWKE GLPTRALQKI QELEGQLDKL KKERQQRQFQ LETLEAALQK QKQKVENEKA
EGANLKRENQ SLMEICENLE KTKQKISHEL QVKESQVNFQ EGQLNSSKKQ IEKLEQELKR
CKSELERSQQ AAQSADVSMS PCTTPQKIFA TPLTPSQYYS GSKYEDLKEK YNKEVEERKR
LEAEVKALQA KKASQATPQS TMNHRDIARH QASSSVFSWQ QEKTPSRLSS SALKTPVRRD
FSASNFSGEQ EVTLSRSTLQ IGNRDANSSF CDNSNLLDQL KAQNQELRSK ISELELRLQG
QEREMKGQVN KLQELQLQVE KAKVELNEKE KVLNKSRDEL VRTTAQYDQA STKCLALEQK
LKKLTEDLSC QRQNAESARC SLEQKIKEKE KEFQEELSRQ QHSFQTLDQE FTQMKAKLTQ
ELQQAKNMHN ILQAELDKVT SVKHQLEKKL EEFKEKFSRT EQTLQASQTK ENELRRSSEE
MKRENSLLKS QSEQRARAVC YLEEELKKAK QRLSQSQNFA EEMRAKNTSQ ETMLRDLQEK
INQQENSLTL EKLKLALADL EKQRDCSQDL LKKREHHIEQ LNEKLSKTER ESEALLSALE
LKKKEYEELK EEKALFSRWK SENEQLLNQM ESEKESLQSK INHLETCLKT QQIKSHEYNE
RVRTLEMERE NLNVEIRNLH NVIDSKTAEA ETQKQAYGEL QQKAEFSDQK HEKEIENMCL
KISQLTGQVE DLEDKLQSLS SEIMDKNQRY QDLHAESESL RDLLKSRDSS AVTNESHQRS
LLASEQQSAV NNSFANIIEE QESVPSERSE CHLETDQSPK SSSMLQNRVV SLEFSLESQK
QMNSDLQKQC EELVQIKGEI EENLMKAEQM HQSFVAETSQ RISKLQEDTS VHQNVVVETL
VTLESKEREL QLLNEKLETE QAEIQELKKS NHLLQESLKE LQLLSETLSL EKKEMSSIIS
LDKKDIEELT QENGTLKEIN AALTQEKMNL LRKTESFSNC IDERDKSISE LSDQYKQERL
TWLQRCEETG NAFRDLSEKY KAEQEKNSKL ECLLNECTSV CEDRKTELGQ LKETFAREHQ
AFVSQLALAE ERNQSLILEL ETVQQALRSE VTDIQSNSKR EADGLKQEIM TLKEEQSKMQ
QEVNALLQEK EHLVELMTTR HEHQHLELEP IQDSVKVAQR KINTRHVQLP TDLEVKDASL
DSYSAQLAQV ESKVRNMELK LQESEGEEYL EHGLQIGELE AGDVQQDTQP RDISGLGNFE
IDPEERYISV LHELSTSQQD NAHLQCSLQT AMNKLDELEK MCEVLQVEKL ELISELNDSR
SECVTAASRM AEEVGKLVNE VKILDDEHGL LQGKCVKETP ESEFGEQQDE QTSVSLNPLD
DSNSHEHLTV SNKEVHMHFA ELQEKFSSLQ SEHKILHDQH CQMSSKMSEL QSYIDTLKAE
NSVLSTSLRN SQGDLVKEVM PGPGEKHFLS LSLSGVTDSP GNAIEASFYK DLLEHMRETS
LLNNLDRTVL AHQSSVEEVS CGSLEGENLT EKEIPSAPVR SVEELETVCQ MYLQSFKKLE
EKIESQGITK NKEIEELERL LSSSREELDC LRKQYLSENE QWQQKLTSVT AEMESKLAAE
KKHTEHLTLE LEVARLQLQG LDLSSRSLLG TDIEDAVRGG NNSCDIRESE DYTSETKERT
PKHEIHQICE KDQDLSLEME KITKTSAIKL IGEWSREQSP ETSPRTPVED TTQGCSECIS
ELSLSGPNAS VPMDFLENQV TIQNLQLQVK ETSNENLRLL HGIKERDQKV ESLLNEIKEL
DSKLSLQEVQ LTTKIEACIE LEKVVEELQK EKSDFSEKLE SFSRDNQRVE SSGGLTSNLE
MGTDKLSHEG IEDEVAKVTD NWRERCLNVE NELQRMKAER GSTEHHALSA EANLEAVQTE
KLFLEKDNEN KQKVITCLEE GLLVVTSERD QLRGELDTLS KENQELDQMS EKMKEKIREL
ESHQDERLHL QEQLQSLEKD SQALSLVRSE LENQIRQLNK ETKSLVRESE SLQTKLSELE
HEKLTVAKAL EAALMEKGEV AVRLSSTQEE VHQLRKGIEK LRVRIEADEK KQLHISEKLK
ESERRNDSLQ DKVETLEREL HMAEENQELV ILDAENSKAE VETLRTQMEL MTESLKTLDL
DLVTIRSEKE NLVKQLQEKQ GQVSELHTLL SSLKNVLEEK EREKIQMKEE SKAEVEILQT
QLKELSEEVA ALCDDRETWE AEEQSPDSPV QEVHQLRNNI GKLKVHLDTD ERKQLHILAK
LKESGHQAAL LKDTVENLER ELEVSGKNQA HVILEAEKSK AEVETLKAKI EETAANLRAL
ELDLVNTRSE KEDLTKELQK EQGRVSELET LNSSYENLLQ EKEQEKEQMK EESKAVVEIL
QTRLKELSEE VAALCDEQET WKAEEQSLSS QVDSLEHEKA QLLQGLDEAK SNYMLLQSSV
NGLIQEVEDG KQKLEKKDEE IRILKNHIQD QEQLVSKLSQ MEGEQQLWEE QRTKLENLMV
ELEQKTQVLQ SKNDTLQDTL EALQNSSKDL EKELELTKME KLSFVEKVNT MTVKETELQK
EMLAMVQKTT ELKEEFSREK NRLTEDLKLV SEEIKSRKGQ LKELMLENSE LEKTLDCAHR
GQMEKRGKMR EEIAEYQLRL QEAEKKHQAL LLDINKQYEM EIQTYREKLT SKEECLSSQK
VEIDLLKSSK EELNNSLKVT TEILEELKKT KMENLKYADK LKKENDRAQG KIKLLIKSCK
QLEEEKEMLQ KEVSHLEAAH EKQKAGTVVD ANVDELMTEM KELKETLEEK TKEADEYLDK
YCSLLISHEK LEKAKEMLET QVARLSSQQS KVNLRSSPSL NSVVPGPSPV PSATEKKLSS
GQNKASGKRQ RSGGIREDGG ETTPSTPEKF SKKSRKAGKS GIHPAEDAED AEPEPEGLPE
VVKKGFADIP TGKTTPYILR RTTMVTRTSP RLAAQKLAPS PLSLDKENLA ETSKPTAGGS
RSQKVKVTQQ SPVDSGTALR EPTTRSLSIS NLPERSSADS PREGLRAKQG RLAPSPEAGP
ESKGSENCRV Q
//
