ID   A0A340X1M9_LIPVE        Unreviewed;       974 AA.
AC   A0A340X1M9;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=General vesicular transport factor p115 {ECO:0000256|ARBA:ARBA00018243};
GN   Name=USO1 {ECO:0000313|RefSeq:XP_007455493.1};
OS   Lipotes vexillifer (Yangtze river dolphin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Lipotidae; Lipotes.
OX   NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007455493.1};
RN   [1] {ECO:0000313|RefSeq:XP_007455493.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC       Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC   -!- SIMILARITY: Belongs to the VDP/USO1/EDE1 family.
CC       {ECO:0000256|ARBA:ARBA00006960}.
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DR   RefSeq; XP_007455493.1; XM_007455431.1.
DR   AlphaFoldDB; A0A340X1M9; -.
DR   STRING; 118797.A0A340X1M9; -.
DR   GeneID; 103075165; -.
DR   CTD; 8615; -.
DR   InParanoid; A0A340X1M9; -.
DR   OrthoDB; 1774at2759; -.
DR   Proteomes; UP000265300; Unplaced.
DR   GO; GO:0000139; C:Golgi membrane; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0048280; P:vesicle fusion with Golgi apparatus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000225; Armadillo.
DR   InterPro; IPR041209; P115_Arm_rpt.
DR   InterPro; IPR006955; Uso1_p115_C.
DR   InterPro; IPR006953; Vesicle_Uso1_P115_head.
DR   PANTHER; PTHR10013; GENERAL VESICULAR TRANSPORT FACTOR P115; 1.
DR   PANTHER; PTHR10013:SF0; GENERAL VESICULAR TRANSPORT FACTOR P115; 1.
DR   Pfam; PF18770; Arm_vescicular; 1.
DR   Pfam; PF04871; Uso1_p115_C; 1.
DR   Pfam; PF04869; Uso1_p115_head; 1.
DR   SMART; SM00185; ARM; 3.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50176; ARM_REPEAT; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265300};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          60..97
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   DOMAIN          351..639
FT                   /note="Vesicle tethering protein Uso1/P115-like head"
FT                   /evidence="ECO:0000259|Pfam:PF04869"
FT   DOMAIN          798..965
FT                   /note="Uso1/p115-like vesicle tethering protein C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04871"
FT   REGION          774..799
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          942..974
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          663..711
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        774..795
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        948..967
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   974 AA;  109140 MW;  8405738892B9C666 CRC64;
     MNFLRGVMGG QSAGPQHTEA ETIQKLCDRV ASSTLLDDRR NAVRALKSLS KKYRLEVGIQ
     AMEHLIHVLQ TDRSDSEIIG YALDTLYNII SNDEEEEVDD VEEENSTRQS EDLGSQFTEI
     FIKQQENVTL LLSLLEEFDF HVRWPGVKLL TSLLKQLGPQ VQQIILVSPM GVSRLMDLLA
     DSREVIRNDG VLLLQALTRS NGAIQKIVAF ENAFERLLDI ITEEGNSDGG IVVEDCLILL
     QNLLKNNNSN QNFFKEGSYI QRMKPWFEVG DENSGWSAQK VTNLHLMLQL VRVLVSPNNP
     PGATSSCQKA MFQCGLLQQL CTILMATGGP ADILTETINT VSEVIRGYQV NQDYFASVNA
     PSNPPRPAIV VLLMSMVNER QPFVLRCAVL YCFQCFLYKN QKGQGEIVST LLPSTIDATG
     NSVSAGQLLC GGLFSTDSLS NWCAAVALAH ALQENATQKE QLLRVQLATS IGNPPVSLLQ
     QCTNILSQGD KIDRRGSKIQ TRVGLLMLLC TWLSNCPIAV THFLHNSANV PFLTGQIAEN
     LGEEEQLVQG LCALLLGISI YFNDNSLESY MKEKLKQLIE KRIGKENFIE KLGFISKHEL
     YSRASQKPQP NFPSPEYMIF DHEFTKLVKE LEGVITKAIY KSSEEDKQEE EVKKTLEQHD
     SIVTHYKNMI REQDLQLEEL KQQISTLKCQ NEQLQTAVTQ QVSQIQQHKD QYNLLKVQLG
     KDNQHQGSYS DGAQMNGIQP EEIGRLREEI EELKSNQELL QSQLAEKDSF IENLKSSQPS
     PGTNEQSSAT ASARDSEQIE ELKQELATLK SQLNSQSSEI TKLQTEKQEL LQKTEAFAKS
     VPIPGESETV IATKTADIEG RLSALLQETK ELKNEIKALS EERTAIKEQL DSSNSTIAIL
     QNEKNKLEVD ITDSKKEQDD LLVLLADQDQ KIFSLKNKLK ELGHPVEEED ELESGDQDDE
     DDEDEDDSKE QGHI
//