ID A0A340X3B2_LIPVE Unreviewed; 1463 AA.
AC A0A340X3B2;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Intraflagellar transport protein 140 homolog {ECO:0000313|RefSeq:XP_007453640.1};
GN Name=IFT140 {ECO:0000313|RefSeq:XP_007453640.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007453640.1};
RN [1] {ECO:0000313|RefSeq:XP_007453640.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium
CC {ECO:0000256|ARBA:ARBA00004138}.
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DR RefSeq; XP_007453640.1; XM_007453578.1.
DR STRING; 118797.A0A340X3B2; -.
DR GeneID; 103072288; -.
DR KEGG; lve:103072288; -.
DR CTD; 9742; -.
DR InParanoid; A0A340X3B2; -.
DR OrthoDB; 5479064at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0005929; C:cilium; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.470; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR15722; IFT140/172-RELATED; 1.
DR PANTHER; PTHR15722:SF7; INTRAFLAGELLAR TRANSPORT PROTEIN 140 HOMOLOG; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF48452; TPR-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 4: Predicted;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Reference proteome {ECO:0000313|Proteomes:UP000265300};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT DOMAIN 39..112
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
SQ SEQUENCE 1463 AA; 165276 MW; 2564272C2E50EB2C CRC64;
MALYFDHRIE APNAVGSPSH ISWHPVHPFL AVASISTASG GSVDIYREQG ECVPDTHIER
SFRVTSLCWH PTRLILAIGW ETGEVVVFNK QDKEQHAVPP TQTADITILN WSPNGNCLVS
GDRLGVLLLW KLDQRGRVQG APLLKHEYGK HLTHCIFRLP PPSEDLVQLA KAAVSGDEKA
LDKFNWRKSG FGSFLKMGPQ EGLSFFVSLT DGTVHYVDKK GRTTWVASTD SSIQTLFYLE
KREVLVAVTE SLLLCLFTVM PEGAAEEVMK VKLSGNMGRQ ANVALINGSL LVTATGEAVL
RFWDLERGEN YVLSPEEKFG FEKGENMNCV SYCRVKGLLA AGTDKGRVAM WRKVPGPQSS
QGVEGKDRWT LQIPTELEGN ITQIKWGSRK SLLAVNSISS VLILREQAMS SHFHQQVAAV
QVSPSLLSVS FLSTGVTHSL RTDMYISGVF ATKDAVAVWN GKQVVIFEPS GATLRSAGTF
LCESPVLAMH EENVYTVEPN RVQVRTWQGT VKQLLPFSET EGNPRFFDIC GNFLVVGTDL
AHFKSFDLSR REAKVHCSCK SLAGLVPGVG GMASLRCNAS GSKISILLSK ADNSPDSRIC
FYDVEMDTVT ILDFKRGQID QRETLSFNGQ ETKKSQALAD ERLTNLVPVS HFWDQSEPRL
FVCEAVQEVP GTQLQPTDRK ALGEASTGPT ADVLVLSFFV SEEHGFLLQD SFLRPPIFQT
LLGIQVPHYY FMRKPGEVDL EDQVDSGSQC IPQTVGRRPL RDFVGLEDCD KPTRDAMLNF
TFFLAVGDMD EAFRSIKLIK SEAVWENMAR MCVKTQRLDV AKVCLGHMGH ARGARALREA
EQEPEPEARV AVLAIQLGML EDAEHLYKNC GRYDLLNRLL QAEGQWQRAI EVAERHDRVH
LRTTYYNYAR HLEASGDCSL ALSYYEKSDT HRFEVPRMLA EDLQALELYI NKMKDKTLWR
WWAQYLESQA EMDAALRYYE LAHDYFSLVR VYCFQGNIQK AAEIASETGN WAASYHLARQ
YESRDEVRQA VHFYTRAQAF NNAIRLCKEH GLDDQLMNLA LLSSPKDMIE AARYYEEKGE
QMDQAVMLYH KAGHFSKALE LAFATQQFVA LQLVAEDLDE KSDPALLARC SDFFLEHSQY
EKAVELLLAA KKYHEALQLC LEQNLTITEE MAEKMTVSKD CKELSEESRR ELLEQIASCC
MRQGNYHLAT KKYTQAGDRL KAMRALLKSG DTEKIVFFAG VSRQKEIYIM AANYLQSLDW
RKDPEIMKSI ISFYTKGRAL DLLAGFYDAC AQVEIDEYQN YDKAHGALTE AYKCLSKAKA
RSPLDQEARL AQLQSKMALV KRFMQARRTY TEDPKESVRQ CKLLLEEPDL DSTVRVGDVY
GFLVERHVQM EDLQTAYKYL EEMRKRVPSA NVSYYVSQRT VDAVHQGLGI PLMWTMPEQM
HHNNMEDHKE LDEEVMEEVE NGP
//
