ID A0A340X3J9_LIPVE Unreviewed; 325 AA.
AC A0A340X3J9;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Brain-specific serine protease 4 {ECO:0000313|RefSeq:XP_007453725.1};
GN Name=PRSS22 {ECO:0000313|RefSeq:XP_007453725.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007453725.1};
RN [1] {ECO:0000313|RefSeq:XP_007453725.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_007453725.1; XM_007453663.1.
DR AlphaFoldDB; A0A340X3J9; -.
DR STRING; 118797.A0A340X3J9; -.
DR GeneID; 103073661; -.
DR KEGG; lve:103073661; -.
DR CTD; 64063; -.
DR InParanoid; A0A340X3J9; -.
DR OrthoDB; 4629979at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00190; Tryp_SPc; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 1.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR InterPro; IPR033116; TRYPSIN_SER.
DR PANTHER; PTHR24253:SF144; BRAIN-SPECIFIC SERINE PROTEASE 4; 1.
DR PANTHER; PTHR24253; TRANSMEMBRANE PROTEASE SERINE; 1.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
DR PROSITE; PS00135; TRYPSIN_SER; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|RuleBase:RU363034};
KW Protease {ECO:0000256|RuleBase:RU363034,
KW ECO:0000313|RefSeq:XP_007453725.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000265300};
KW Serine protease {ECO:0000256|RuleBase:RU363034};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 34..325
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016445666"
FT DOMAIN 50..290
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
FT REGION 295..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 310..325
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 325 AA; 35103 MW; CB66DCFCFCE9CC95 CRC64;
MVVPETLPAL GRHYVRIVTS LLLLAAPATL AAAKTAGPPA CGKPQHLNRI VGGEDSTDAE
WPWLVSIQKN GTHYCAGSLL TNRWVLTAAH CFKGHLNKPA LFSVLLGAWK LGNPGPRSQE
VGIAWVKPHP VYSWKEGARA DIALVRLEHS IQFSERILPI CLPDSSVHLL PDTNCWVAGW
GSIHDGVPLP HPQTLQKLKV PIIDSAVCSR LYWRGAGQGA ITEDMLCAGY LEGERDACLG
DSGGPLMCQV ERTWLLAGVI SWGEGCAERN RPGVYISLAA HRSWVQRIVQ GVQLHGHSQG
SGPTGRRGRA LGARRARRAA RGRGV
//
