ID A0A340X4N2_LIPVE Unreviewed; 268 AA.
AC A0A340X4N2;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Neuferricin {ECO:0000256|ARBA:ARBA00039568};
DE AltName: Full=Cytochrome b5 domain-containing protein 2 {ECO:0000256|ARBA:ARBA00042241};
GN Name=LOC103073933 {ECO:0000313|RefSeq:XP_007454234.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007454234.1};
RN [1] {ECO:0000313|RefSeq:XP_007454234.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Heme-binding protein which promotes neuronal but not
CC astrocyte differentiation. {ECO:0000256|ARBA:ARBA00037690}.
CC -!- SIMILARITY: Belongs to the cytochrome b5 family. MAPR subfamily.
CC {ECO:0000256|ARBA:ARBA00038357}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_007454234.1; XM_007454172.1.
DR AlphaFoldDB; A0A340X4N2; -.
DR STRING; 118797.A0A340X4N2; -.
DR GeneID; 103073933; -.
DR KEGG; lve:103073933; -.
DR InParanoid; A0A340X4N2; -.
DR OrthoDB; 2872279at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR Gene3D; 3.10.120.10; Cytochrome b5-like heme/steroid binding domain; 1.
DR InterPro; IPR001199; Cyt_B5-like_heme/steroid-bd.
DR InterPro; IPR036400; Cyt_B5-like_heme/steroid_sf.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR10281; MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED; 1.
DR PANTHER; PTHR10281:SF4; NEUFERRICIN; 1.
DR Pfam; PF00173; Cyt-b5; 1.
DR SMART; SM01117; Cyt-b5; 1.
DR SUPFAM; SSF55856; Cytochrome b5-like heme/steroid binding domain; 1.
DR PROSITE; PS51318; TAT; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000265300}.
FT DOMAIN 42..138
FT /note="Cytochrome b5 heme-binding"
FT /evidence="ECO:0000259|SMART:SM01117"
FT REGION 222..252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 268 AA; 29656 MW; 3C1D6926F93ED2A0 CRC64;
MLRLGRRGLW LGLAAAAAAA AAAAMATRLM GWWSPRADFR LFIPEELARC RGRPGDPGLY
LALLGRVYDV SSGRRHYEPG AHYSGFAGRD ASRAFVTGDY SEGGLVDDVS DLSFSEMLTL
QSWLSFYEKN YEFIGRVTGR FYGEDGLPTP ELTQAEAMIT KGLEANKQEL KEKQKFPPCN
AEWSSTRGSR FWCSQRSGGV SRDWTGVPRK LFKPGAKEPH CVCVRTTGPP SDQTPDNPTH
RSRGDLDHPN LEEYTGCPPL AITCYVPL
//
