ID   A0A340X5S6_LIPVE        Unreviewed;       728 AA.
AC   A0A340X5S6;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Solute carrier organic anion transporter family member {ECO:0000256|RuleBase:RU362056};
GN   Name=SLCO1C1 {ECO:0000313|RefSeq:XP_007454659.1};
OS   Lipotes vexillifer (Yangtze river dolphin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Lipotidae; Lipotes.
OX   NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007454659.1};
RN   [1] {ECO:0000313|RefSeq:XP_007454659.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362056};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU362056}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the organo anion transporter (TC 2.A.60) family.
CC       {ECO:0000256|ARBA:ARBA00009657, ECO:0000256|RuleBase:RU362056}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|RuleBase:RU362056}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_007454659.1; XM_007454597.1.
DR   AlphaFoldDB; A0A340X5S6; -.
DR   STRING; 118797.A0A340X5S6; -.
DR   GeneID; 103070456; -.
DR   KEGG; lve:103070456; -.
DR   CTD; 53919; -.
DR   InParanoid; A0A340X5S6; -.
DR   OrthoDB; 2874223at2759; -.
DR   Proteomes; UP000265300; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd17459; MFS_SLCO1C_OATP1C; 1.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR   InterPro; IPR002350; Kazal_dom.
DR   InterPro; IPR036058; Kazal_dom_sf.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR004156; OATP.
DR   NCBIfam; TIGR00805; oat; 1.
DR   PANTHER; PTHR11388; ORGANIC ANION TRANSPORTER; 1.
DR   PANTHER; PTHR11388:SF99; SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1C1; 1.
DR   Pfam; PF07648; Kazal_2; 1.
DR   Pfam; PF03137; OATP; 1.
DR   SUPFAM; SSF100895; Kazal-type serine protease inhibitors; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR   PROSITE; PS51465; KAZAL_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Ion transport {ECO:0000256|RuleBase:RU362056};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362056};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265300};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362056};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362056}; Transport {ECO:0000256|RuleBase:RU362056}.
FT   TRANSMEM        111..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        221..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        271..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        355..373
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        393..413
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        425..445
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        550..575
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        587..608
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   DOMAIN          470..525
FT                   /note="Kazal-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51465"
SQ   SEQUENCE   728 AA;  80358 MW;  9EF9DFF941120BA9 CRC64;
     MDTSSKENIQ LFSKNSMQPV GRPSFKTEYP SSEEKQPCCG ELKVFLGALS FVYFAKALAE
     GYLKSTITQI ERRFDIPSSL VGVIDGSFEI GNLLVITFVS YFGAKLHRPK IIGAGCLIMG
     VGTLLIAMPQ FFMEQYRYER YSPFSNSTFS ISPCFLGSNS PLPISVMEKS QSKINNECEI
     DASSSMWAYV FLGNLLRGIG ETPIQPLGIA YLDDFANEDN AAFYIGCVQT VAIIGPIFGF
     LLGSLCAKLY VDIGFVNLDH ITITPKDPQW VGAWWLGYLI AGSISLLAAV PFWYLPRSLP
     RPRSREDSNS SSEKSKFIMD DHTDYQTPLG EKAKIMEMAR DFLPSLKSLF GNPVYFLYLC
     ASTVQFNSLF GMVTYKPKYI EQQYGQSSSK ANFVIGLINI PAVAFGIFSG GIVMKKFRIS
     VCGAAKLYLG SSVLGYLLFL SLFALGCENS DVAGLTVSYQ GTKPVSYHER ALFSDCNSRC
     KCSETKWEPM CGANGITYAS ACLAGCQTST GSGKTTIFNN CTCVGIATSK SGNSSGMVGR
     CQKDNGCPKM FLYFLVISVI TSYTLSLGGI PGYILLLRCI KPQLKSFALG IYTLAVRVLA
     GIPAPVYFGV LIDTSCLKWG FKRCGSRGSC RLYDSNAFRY RIKLIPTSHG YHIPGLHNAI
     GTNNPHVVSL LTYVSGTNHD PWHNVHFPKY CSTFHFKEKV CFKTQKLQNQ ERKNNGVYKN
     QEGKLYDK
//