ID A0A340X9H7_LIPVE Unreviewed; 267 AA.
AC A0A340X9H7;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=OX-2 membrane glycoprotein {ECO:0000313|RefSeq:XP_007458223.1};
GN Name=CD200 {ECO:0000313|RefSeq:XP_007458223.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007458223.1};
RN [1] {ECO:0000313|RefSeq:XP_007458223.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007458223.1; XM_007458161.1.
DR AlphaFoldDB; A0A340X9H7; -.
DR STRING; 118797.A0A340X9H7; -.
DR GeneID; 103083872; -.
DR KEGG; lve:103083872; -.
DR CTD; 4345; -.
DR InParanoid; A0A340X9H7; -.
DR OrthoDB; 3820664at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0098632; F:cell-cell adhesion mediator activity; IEA:InterPro.
DR GO; GO:0043031; P:negative regulation of macrophage activation; IEA:InterPro.
DR GO; GO:0050776; P:regulation of immune response; IEA:InterPro.
DR CDD; cd05846; IgV_1_MRC-OX-2_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR033321; CD200_Ig_V_dom.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR013151; Immunoglobulin.
DR InterPro; IPR047164; OX2G-like.
DR PANTHER; PTHR46841; OX-2 MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR46841:SF3; OX-2 MEMBRANE GLYCOPROTEIN; 1.
DR Pfam; PF00047; ig; 2.
DR SMART; SM00409; IG; 2.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265300};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..267
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016353513"
FT TRANSMEM 231..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 45..130
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 141..228
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 267 AA; 30290 MW; BED16AEF3ABD8EB7 CRC64;
MEWLVLRRLF CHLSTFQLIW FLAAMMFCRA QVETQDVREL LNAPASLRCS LQNPQEVLIV
TWQKIKAVSP ENMITFSQNH GVVVQPAYKD KINITQLGLM NSTITFWNTT LEDEGCYKCL
FNTFGSGKIS GIACLTLFVQ PTVFLHYKLS EDHLNITCSA NARPAPMISW KVSGSETENS
TEILSHPNGT TSVTSILQIK DPKSQVGKEV ICQVLHLGTV TDYRETVNKG FWFSVPLLLS
IVSLVILLVL ISILLYWKHR RNQDREP
//
