ID A0A340XC24_LIPVE Unreviewed; 533 AA.
AC A0A340XC24;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=E3 ubiquitin-protein ligase TRIM68 isoform X1 {ECO:0000313|RefSeq:XP_007456580.1};
GN Name=TRIM68 {ECO:0000313|RefSeq:XP_007456580.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007456580.1};
RN [1] {ECO:0000313|RefSeq:XP_007456580.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007456580.1; XM_007456518.1.
DR AlphaFoldDB; A0A340XC24; -.
DR STRING; 118797.A0A340XC24; -.
DR GeneID; 103074222; -.
DR KEGG; lve:103074222; -.
DR CTD; 55128; -.
DR InParanoid; A0A340XC24; -.
DR OrthoDB; 3453019at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd16610; RING-HC_TRIM68_C-IV; 1.
DR CDD; cd13733; SPRY_PRY_C-I_1; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR042656; TRIM68_RING-HC.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF89; E3 UBIQUITIN-PROTEIN LIGASE TRIM68; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000265300};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 64..109
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 141..182
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 333..529
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
SQ SEQUENCE 533 AA; 60727 MW; 9D1B86C1FCF87A2E CRC64;
MLRTLGRGNQ AGVSTFGFSL GALLPAEKGA FSGSSWFYSC SEEGVTGAMD PAALVEAVVE
EVACPICMTF LKEPVSIDCG HSFCHNCLSG LWEVPGESQN WGYSCPLCRA PVQPRNLRPN
WQLANVVEKV RRLGLHPGMG LKGDVCKTHE EQLKMFCKED GLIVCEACGR SPEHEAHSVV
PMEDVAWDYK WKLHEALEHL RKEQEEAWKL EVGERKRTAN WKIQVETRKQ SIIWEFEKYR
RLLKKKQPPG RRLEVEAAAA LASLEQEEGE TTQKLGVSHN ALIQQSRVLW RMIAELEERS
QRPVRWMLQG IQEVLNRSKS WSLQRPEPVS LELKTDCRVL GLREILKTYA ADVRLDPDTA
YSRLIVSEDR KCVRYGDTKQ KLPDNPERFY RYNIVLGSQC ISSGRHYWEV EVGDRSEWGL
GVCKENVDRK EVVYLSPHYG FWVIRLRKGD EYRAGTDEYP LLSLPVPPRR VGVFLDYEAH
DISFYNVTDS GSHIFTFPHY PFPGRLLPYF SPCYSIGANN TAPLAICSLD GDD
//
