ID A0A340XEK9_LIPVE Unreviewed; 706 AA.
AC A0A340XEK9;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Amyloid beta A4 precursor protein-binding family B member 1 isoform X2 {ECO:0000313|RefSeq:XP_007459868.1};
DE SubName: Full=Amyloid beta A4 precursor protein-binding family B member 1 isoform X3 {ECO:0000313|RefSeq:XP_007459869.1};
GN Name=APBB1 {ECO:0000313|RefSeq:XP_007459868.1,
GN ECO:0000313|RefSeq:XP_007459869.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007459868.1};
RN [1] {ECO:0000313|RefSeq:XP_007459868.1, ECO:0000313|RefSeq:XP_007459869.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007459868.1; XM_007459806.1.
DR RefSeq; XP_007459869.1; XM_007459807.1.
DR GeneID; 103079605; -.
DR CTD; 322; -.
DR OrthoDB; 5404780at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0001540; F:amyloid-beta binding; IEA:InterPro.
DR CDD; cd01272; PTB1_Fe65; 1.
DR CDD; cd01271; PTB2_Fe65; 1.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR039576; APBB1/2/3.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006020; PTB/PI_dom.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR14058; AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B; 1.
DR PANTHER; PTHR14058:SF5; AMYLOID BETA PRECURSOR PROTEIN BINDING FAMILY B MEMBER 1; 1.
DR Pfam; PF00640; PID; 2.
DR Pfam; PF00397; WW; 1.
DR SMART; SM00462; PTB; 2.
DR SMART; SM00456; WW; 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS01179; PID; 2.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265300}.
FT DOMAIN 251..283
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 368..505
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT DOMAIN 538..695
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 49..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 131..254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 274..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 316..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..172
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..247
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 706 AA; 76493 MW; 381BD632EA44B264 CRC64;
MSVPSSLSQS AINANSHGGP ALSLPLPLHA AHNQLLNAKL QATAVGPKDL RSAMGEGGGP
EPGPANAKWL KEGQNQLRRA ATAHRDQNRN VTLTLAEEAS QEPEMAPLGP KGLMHLYSEL
ELSAHNAANR GLRGPGLIIG TREQGPDEGE EKAAGEAEED DEEEEEEDDD LSSPPGLPAP
LGAAEVPPGP QALADGPREH SKSASLLFGM RNSAASDEDS SWATLSQGSP SYGSPEDTDS
FWNPNAFETD SDLPAGWMRV QDTSGTYYWH IPTGTTQWEP PGQASPSQGS SPREESQLTW
TGFTHGEGFE DGEFWKDEPS EEAPMDLGLQ DPEEGTLPFP AQSLSPEPLP REEEKLRPRN
ANPGTKCFAV RSLGWVEMTE EELAPGRSSV AVNNCIRQLS YHKNNLHDPM SGGWGEGKDL
LLQLEDETLK LVEPHSQALL HAQPIVSIRV WGVGRDSGRD FAYVARDKLT QMLKCHVFRC
EAPAKNIATS LHEICSKIMA ERRNARCLVN GLSLDHSKLV DVPFQVEFPA PKNELVQKFQ
VYYLGNVPVA KPVGVDVING ALESVLSSSS REQWTPSHVS VAPATLTILH QQTEAVLGEC
RVRFLSFLAV GRDVHTFAFI MAAGPASFCC HMFWCEPNAA SLSEAVQAAC MLRYQKCLDA
RSQASTSCLP APPAESVARR VGWTVRRGVQ SLWGSLKPKR LGAHTP
//
