ID A0A340XEZ3_LIPVE Unreviewed; 780 AA.
AC A0A340XEZ3;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Protein phosphatase 1 regulatory subunit 21 {ECO:0000256|ARBA:ARBA00020102};
DE AltName: Full=Coiled-coil domain-containing protein 128 {ECO:0000256|ARBA:ARBA00031617};
DE AltName: Full=KLRAQ motif-containing protein 1 {ECO:0000256|ARBA:ARBA00031361};
GN Name=PPP1R21 {ECO:0000313|RefSeq:XP_007460046.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007460046.1};
RN [1] {ECO:0000313|RefSeq:XP_007460046.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Early endosome {ECO:0000256|ARBA:ARBA00004412}.
CC Endosome {ECO:0000256|ARBA:ARBA00004177}.
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DR RefSeq; XP_007460046.1; XM_007459984.1.
DR AlphaFoldDB; A0A340XEZ3; -.
DR STRING; 118797.A0A340XEZ3; -.
DR GeneID; 103089886; -.
DR KEGG; lve:103089886; -.
DR CTD; 129285; -.
DR InParanoid; A0A340XEZ3; -.
DR OrthoDB; 2882462at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
DR InterPro; IPR040024; PPP1R21.
DR InterPro; IPR049372; PPP1R21_C.
DR InterPro; IPR019343; PPP1R21_N.
DR InterPro; IPR019348; PPP1R21_six_helix.
DR PANTHER; PTHR21448:SF0; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 21; 1.
DR PANTHER; PTHR21448; SMOOTH MUSCLE MYOSIN HEAVY CHAIN-RELATED; 1.
DR Pfam; PF10205; KLRAQ; 1.
DR Pfam; PF21636; PPP1R21_C; 1.
DR Pfam; PF10212; PPP1R21_helical; 1.
DR SMART; SM01254; KLRAQ; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Reference proteome {ECO:0000313|Proteomes:UP000265300}.
FT DOMAIN 11..112
FT /note="Protein phosphatase 1 regulatory subunit 21 N-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM01254"
FT REGION 84..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 753..780
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 3..72
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 137..196
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 558..592
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 696..730
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 754..771
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 780 AA; 88139 MW; 7D8667828069BF84 CRC64;
MASAELQGKY QKLAQEYSKL RAQNQVLKKG VVDEQANSAA LKEQLKMKDQ SLRKLQQEMD
SLTFRNLQLA KRVELLQDEL ALSEPRGKKN KKSGESSSQL SQEQKSVFDE DLQKKIEENE
RLHIQFFEAD EQHKHVEAEL RSRLATLEME AAQHQAVVDG LTRKYMETIE KLQNDKAKLE
VKSQTLEKEA KECRLRTEEC QLQLKNLHED LSSRLEESLS IINEKVPFND TKYSQYNALN
VPVHNRRHQL KMRDIAGQAL AFVQDLVKGL LNFHTYTEQR IQIFPVDSAI DTISPLNQKF
SQYLHENASY VRPLEEGMLH LFESITEDTV TVLETTVKLK TFSEHLTSYI CFLRKILPYQ
LKSLEEECEA SLCTSALRAR NLELSQDMKK MTAVFEKLQT YIGLLALPST EPDGLLRTNY
SSVLTNVGAA LHGFHDVMKD ISKHYSQKAT IEHELPTATQ KLITTNDCIL SSVVALTNGA
GKIASFFSNN VDYFIASLSY GPKTASGFIS PLSAECMLQY KKKAAAYMKA LRKPLLESVP
YEEALANRRV LLSSTESREG LAQQVQQSLE KISKLEQEKE HWMLEAQLAK IKLEKENQRT
ADKLKSTSSG QAVGVAQEGA AVVTAAGQED ASAKAVPVPV HSTSLIGILT WTSDSEAPDV
ESREDLIRNH YMARIVELTS QLQLADSKSV HFYAECRALS KRLALAEKSK EALAEEMKVA
SQNNSRLQDE LTTTKRSYED QLSMMSDHLC SMNETLSKQR EEIDTLKMSS KGNSKKNKSR
//
