ID A0A340XF36_LIPVE Unreviewed; 738 AA.
AC A0A340XF36;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Protein phosphatase 1 regulatory subunit 21 {ECO:0000256|ARBA:ARBA00020102};
DE AltName: Full=Coiled-coil domain-containing protein 128 {ECO:0000256|ARBA:ARBA00031617};
DE AltName: Full=KLRAQ motif-containing protein 1 {ECO:0000256|ARBA:ARBA00031361};
GN Name=PPP1R21 {ECO:0000313|RefSeq:XP_007460048.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007460048.1};
RN [1] {ECO:0000313|RefSeq:XP_007460048.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Early endosome {ECO:0000256|ARBA:ARBA00004412}.
CC Endosome {ECO:0000256|ARBA:ARBA00004177}.
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DR RefSeq; XP_007460048.1; XM_007459986.1.
DR AlphaFoldDB; A0A340XF36; -.
DR GeneID; 103089886; -.
DR CTD; 129285; -.
DR OrthoDB; 2882462at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
DR InterPro; IPR040024; PPP1R21.
DR InterPro; IPR049372; PPP1R21_C.
DR InterPro; IPR019343; PPP1R21_N.
DR InterPro; IPR019348; PPP1R21_six_helix.
DR PANTHER; PTHR21448:SF0; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 21; 1.
DR PANTHER; PTHR21448; SMOOTH MUSCLE MYOSIN HEAVY CHAIN-RELATED; 1.
DR Pfam; PF10205; KLRAQ; 1.
DR Pfam; PF21636; PPP1R21_C; 1.
DR Pfam; PF10212; PPP1R21_helical; 1.
DR SMART; SM01254; KLRAQ; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Reference proteome {ECO:0000313|Proteomes:UP000265300}.
FT DOMAIN 11..112
FT /note="Protein phosphatase 1 regulatory subunit 21 N-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM01254"
FT REGION 84..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 711..738
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 3..72
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 137..196
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 527..561
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 654..688
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 712..729
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 738 AA; 83497 MW; 5591BC553E92887A CRC64;
MASAELQGKY QKLAQEYSKL RAQNQVLKKG VVDEQANSAA LKEQLKMKDQ SLRKLQQEMD
SLTFRNLQLA KRVELLQDEL ALSEPRGKKN KKSGESSSQL SQEQKSVFDE DLQKKIEENE
RLHIQFFEAD EQHKHVEAEL RSRLATLEME AAQHQAVVDG LTRKYMETIE KLQNDKAKLE
VKSQTLEKEA KECRLRTEEC QLQLKNLHED LSSRLEESLS IINEKVPFND TKYSQYNALN
VPVHNRRHQL KMRDIAGQAL AFVQDLVKGL LNFHTYTEQR IQIFPVDSAI DTISPLNQKF
SQYLHENASY VRPLEEGMLH LFESITEDTV TVLETTVKLK TFSEHLTSYI CFLRKILPYQ
LKSLEEECEA SLCTSALRAR NLELSQDMKK MTAVFEKLQT YIGLLALPST EPDGLLRTNY
SSVLTNVGAA LHGFHDVMKD ISKHYSQKAT IEHELPTATQ KLITTNDCIL SSVVALTNGA
GKIASFFSNN VDYFIASLSY GPKTASGFIS PLSAECMLQY KKKAAAYMKA LRKVQQSLEK
ISKLEQEKEH WMLEAQLAKI KLEKENQRTA DKLKSTSSGQ AVGVAQEGAA VVTAAGQEDA
SAKAVPVPVH STSLAPDVES REDLIRNHYM ARIVELTSQL QLADSKSVHF YAECRALSKR
LALAEKSKEA LAEEMKVASQ NNSRLQDELT TTKRSYEDQL SMMSDHLCSM NETLSKQREE
IDTLKMSSKG NSKKNKSR
//
