ID   A0A340XID7_LIPVE        Unreviewed;       641 AA.
AC   A0A340XID7;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Isthmin-2 {ECO:0000313|RefSeq:XP_007459857.1};
GN   Name=ISM2 {ECO:0000313|RefSeq:XP_007459857.1};
OS   Lipotes vexillifer (Yangtze river dolphin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Lipotidae; Lipotes.
OX   NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007459857.1};
RN   [1] {ECO:0000313|RefSeq:XP_007459857.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the isthmin family.
CC       {ECO:0000256|ARBA:ARBA00010198}.
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DR   RefSeq; XP_007459857.1; XM_007459795.1.
DR   AlphaFoldDB; A0A340XID7; -.
DR   STRING; 118797.A0A340XID7; -.
DR   GeneID; 103075370; -.
DR   KEGG; lve:103075370; -.
DR   CTD; 145501; -.
DR   InParanoid; A0A340XID7; -.
DR   OrthoDB; 5399085at2759; -.
DR   Proteomes; UP000265300; Unplaced.
DR   Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 1.
DR   InterPro; IPR005533; AMOP_dom.
DR   InterPro; IPR000884; TSP1_rpt.
DR   InterPro; IPR036383; TSP1_rpt_sf.
DR   PANTHER; PTHR10239; ISTHMIN-2; 1.
DR   PANTHER; PTHR10239:SF28; ISTHMIN-2; 1.
DR   Pfam; PF03782; AMOP; 1.
DR   Pfam; PF00090; TSP_1; 1.
DR   SMART; SM00723; AMOP; 1.
DR   SMART; SM00209; TSP1; 1.
DR   SUPFAM; SSF82895; TSP-1 type 1 repeat; 1.
DR   PROSITE; PS50856; AMOP; 1.
DR   PROSITE; PS50092; TSP1; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265300};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           27..641
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5016294164"
FT   DOMAIN          466..629
FT                   /note="AMOP"
FT                   /evidence="ECO:0000259|PROSITE:PS50856"
FT   REGION          56..100
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          291..388
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        292..307
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        308..329
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   641 AA;  69608 MW;  6D1499DBC170F1AE CRC64;
     MPRLPGRAAL PLCVVLLTAL LAAVRALPLR KPRGPGWSHV RLAEVSGAAR AARLWVPAPP
     APSSGRAGSR TGTRVAAPEC EGRDPRTSAG IGRWPGAPDL RKTPPGCEAD ASSTPFPAPA
     MTTTNVIAKC PKMKPGICAQ EAGASKSARK AADPELLLPQ VSASPDPSSP REEETPLLSR
     AHLQAGLCRH RRWALTEPAA LTLDKTSLPG TLEDAPLLLE LQKLPGLANT DLSAPNPSIQ
     VTIEVVEDPQ SEVEMDLLAE PNNRWSQGAP SWLPAKELFW PLFWGYLEGE EGRPSLKGRA
     PGEEEDYPPE YHESEDQEDH DEEDDDDQEH GFSGAAGGWE RGWLPPGDRA FKEPDSSGAS
     WPGPYPPKEG VPSANSHQGT PWAPLPHPWL PALTQTRLQE EWSPWFPCSG SCGSGSQQRT
     RPCGYACTAT ESRACDLPPC PGAEDKDPLG FPSEGWQPLA HNATDMLSPD VDSCEKWLNC
     KSDFLAKYLS QVLRDLPSCP CAYPLEAMSS AVSLQDEHQG RSFRWRDASG PRERLDVYQP
     TARFCLRSLL SGESSTLAAQ HCCYDAGSRL LTRGKGAGAP DLVSTDFSPE LHFKVDTLPW
     ILCKGDWSRY HAVRPPNNGR ACTDNPPEEE YLAQLQEAKE F
//