ID A0A340XJS0_LIPVE Unreviewed; 885 AA.
AC A0A340XJS0;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=DNA polymerase kappa {ECO:0000256|ARBA:ARBA00016178};
GN Name=POLK {ECO:0000313|RefSeq:XP_007461668.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007461668.1};
RN [1] {ECO:0000313|RefSeq:XP_007461668.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007461668.1; XM_007461606.1.
DR AlphaFoldDB; A0A340XJS0; -.
DR STRING; 118797.A0A340XJS0; -.
DR GeneID; 103080788; -.
DR KEGG; lve:103080788; -.
DR CTD; 51426; -.
DR InParanoid; A0A340XJS0; -.
DR OrthoDB; 146204at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd03586; PolY_Pol_IV_kappa; 1.
DR Gene3D; 1.10.150.810; -; 2.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 2.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR HAMAP; MF_01113; DNApol_IV; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR022880; DNApol_IV.
DR InterPro; IPR024728; PolY_HhH_motif.
DR InterPro; IPR006642; Rad18_UBZ4.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR11076:SF33; DNA POLYMERASE KAPPA; 1.
DR PANTHER; PTHR11076; DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR Pfam; PF11798; IMS_HHH; 1.
DR PIRSF; PIRSF036603; DPol_eta; 1.
DR SMART; SM00734; ZnF_Rad18; 2.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50173; UMUC; 1.
DR PROSITE; PS51908; ZF_UBZ4; 2.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|PROSITE-
KW ProRule:PRU01256};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|PROSITE-
KW ProRule:PRU01256}; DNA synthesis {ECO:0000256|ARBA:ARBA00022634};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000265300};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU01256}.
FT DOMAIN 117..372
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT DOMAIN 635..665
FT /note="UBZ4-type"
FT /evidence="ECO:0000259|PROSITE:PS51908"
FT DOMAIN 791..821
FT /note="UBZ4-type"
FT /evidence="ECO:0000259|PROSITE:PS51908"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 664..691
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 828..855
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 834..852
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 885 AA; 100342 MW; 10E8F46AFA26DE79 CRC64;
MDGTEGKNDS TKRKNDSTNE KNDNYKDDLL LRVGLNDNKA GMEGLDKEKI NKIIMEATKG
SRFYGNELKK EKQVNQRIEN MMQQKAQITS QQLRKAQLQV DRFAMELEHS RDLNNTIVHI
DMDAFYAAVE MRDNPELKDK PIAVGSVSML STSNYHARRF GVRAAMPGFI AKRLCPQLII
VPPNFDKYRA VSREVKEILA DYDPNFMAMS LDEAYVNITK HLEERQNWPE DKRKYFIKTG
NSLENDKPGK EVNKLREQER SISPLLFEDS PPDLQSPGNA FQVNFEELNN LQILQNSIVF
GTSAEEVVKE IRFRIEQKTT LTASAGIAPN TMLAKVCSDK NKPNGQYQIL PNRQAVMDFI
KDLPIRKVSG IGKVTEKMLK ALGIITCTEL YQQRALLSLL FSETSWHYFL HISLGLGSTH
LARDGERKSM SVERTFSEIS KAEEQYSLCQ ELCSELAQDL QKEGLKGRTV TIKLKNVNFE
VKTRASTVSS VVSTAEEIFA IAKELLRTEI DADFPHPLRL RLMGVRLSGF PNEEEKKCQQ
RSIIGFLQPG NQALSATRCI PEKTDKDQFL KPLEMSQKKS FFDKKRSERN WSYQDTFKCE
TVDKQSLQTS QFFQVLKKRM SENLETLENS DNCHIFTCPV CFREQGSISL EAFNKHVDAC
LEGPSISGNS KMSSRSHASS TEVNEKENVH DSVSVCEKQD YETHQKNTEI TSVDSVELAE
TTGNPSNTEG VDVLSNKHSE EECSSLPSKS FNMEHCPQNC CAVSLENEDV ASLRRKEPLQ
PYLYEVISDQ VLICPVCNLE QKTSDLTLFN VHVDVCLNKG IIQELRKDKV NPVNQPKEST
TSTDNSGKVQ KIGTKANRPG LMTKYSASKK TKPNSPRHTL DIFFK
//
