ID A0A340XKU4_LIPVE Unreviewed; 546 AA.
AC A0A340XKU4;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Transcription factor p65 isoform X3 {ECO:0000313|RefSeq:XP_007462053.1};
GN Name=RELA {ECO:0000313|RefSeq:XP_007462053.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007462053.1};
RN [1] {ECO:0000313|RefSeq:XP_007462053.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007462053.1; XM_007461991.1.
DR AlphaFoldDB; A0A340XKU4; -.
DR GeneID; 103087304; -.
DR CTD; 5970; -.
DR OrthoDB; 1059550at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd01177; IPT_NFkappaB; 1.
DR CDD; cd07885; RHD-n_RelA; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.40.340; Rel homology domain (RHD), DNA-binding domain; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR033926; IPT_NFkappaB.
DR InterPro; IPR000451; NFkB/Dor.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR030495; RelA_RHD_N.
DR InterPro; IPR030492; RHD_CS.
DR InterPro; IPR032397; RHD_dimer.
DR InterPro; IPR011539; RHD_DNA_bind_dom.
DR InterPro; IPR037059; RHD_DNA_bind_dom_sf.
DR PANTHER; PTHR24169; NUCLEAR FACTOR NF-KAPPA-B PROTEIN; 1.
DR PANTHER; PTHR24169:SF1; TRANSCRIPTION FACTOR P65; 1.
DR Pfam; PF16179; RHD_dimer; 1.
DR Pfam; PF00554; RHD_DNA_bind; 1.
DR PRINTS; PR00057; NFKBTNSCPFCT.
DR SMART; SM00429; IPT; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS01204; REL_1; 1.
DR PROSITE; PS50254; REL_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265300}.
FT DOMAIN 16..187
FT /note="RHD"
FT /evidence="ECO:0000259|PROSITE:PS50254"
FT REGION 308..345
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 500..520
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 546 AA; 59739 MW; F12D43D0D2462655 CRC64;
MDDLFPLIFP AEPAQASGPY VEIIEQPKQR GMRFRYKCEG RSAGSIPGER STDTTKTHPT
IKINGYTGPG TVRISLVTKD PPHRPHPHEL VGKDCRDGFY EAELCPDRCI HSFQNLGIQC
VKKRDLEQAI SQRIQTNNNP FQEEQRGDYD LNAVRLCFQV TVRDPAGRPL RLSPALSHPI
FDNRAPNTAE LKICRVNRNS GSCLGGDEIF LLCDKVQKED IEVYFTGPGW EARGSFSQAD
VHRQVAIVFR TPPYADPSLQ APVRVSMQLR RPSDRELSEP MEFQYLPDTD DRHRIEEKRK
RTYETFKSIM KKSPFNGPTD HRPPTRRIAV PSRSSTSVPK PPPQPYPFTP SLSTINFEEF
SPMVFPSGQI SSQTSALAPA PALVLAQAPA PAPAMASALA QAPAPVLAPG LAQAVTPPAP
KTNPAGEGTL TEALLQLQFD ADEDLGALLG NSTDPAVFTD LASVDNSEFQ QLLNQGVPMA
PHTAEPMLME YPEAITRLVT GSQRPPDPAP TPLGASGLTN GLLSGDEDFS SIADMDFSAL
LSQISS
//
