ID A0A340XL77_LIPVE Unreviewed; 421 AA.
AC A0A340XL77;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Acyl-coenzyme A thioesterase 6-like {ECO:0000313|RefSeq:XP_007459775.1};
GN Name=LOC103073519 {ECO:0000313|RefSeq:XP_007459775.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007459775.1};
RN [1] {ECO:0000313|RefSeq:XP_007459775.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the C/M/P thioester hydrolase family.
CC {ECO:0000256|ARBA:ARBA00006538}.
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DR RefSeq; XP_007459775.1; XM_007459713.1.
DR AlphaFoldDB; A0A340XL77; -.
DR STRING; 118797.A0A340XL77; -.
DR GeneID; 103073519; -.
DR KEGG; lve:103073519; -.
DR InParanoid; A0A340XL77; -.
DR OrthoDB; 5356064at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0016790; F:thiolester hydrolase activity; IEA:InterPro.
DR GO; GO:0006637; P:acyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 2.60.40.2240; Acyl-CoA thioester hydrolase/BAAT N-terminal domain; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR016662; Acyl-CoA_thioEstase_long-chain.
DR InterPro; IPR014940; BAAT_C.
DR InterPro; IPR006862; Thio_Ohase/aa_AcTrfase.
DR InterPro; IPR042490; Thio_Ohase/BAAT_N.
DR PANTHER; PTHR10824:SF17; ACYL-COENZYME A THIOESTERASE 6; 1.
DR PANTHER; PTHR10824; ACYL-COENZYME A THIOESTERASE-RELATED; 1.
DR Pfam; PF08840; BAAT_C; 1.
DR Pfam; PF04775; Bile_Hydr_Trans; 1.
DR PIRSF; PIRSF016521; Acyl-CoA_hydro; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000265300}.
FT DOMAIN 16..140
FT /note="Acyl-CoA thioester hydrolase/bile acid-CoA amino
FT acid N-acetyltransferase"
FT /evidence="ECO:0000259|Pfam:PF04775"
FT DOMAIN 204..411
FT /note="BAAT/Acyl-CoA thioester hydrolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08840"
FT ACT_SITE 232
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT ACT_SITE 326
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT ACT_SITE 360
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
SQ SEQUENCE 421 AA; 46314 MW; C37BF9D34A4A12B9 CRC64;
MAATVTLEPA GRCRWDEPVR IAVRGLAPGQ PVTLRASLRD EKDTLFRAHA RYCADAHGQL
DLERAPALGG SFTGLEPMGL LWALEPEKPL LRLVKRDVQT PFAVELEVLD GHDPEAGGLL
GRAVHERDFL APGVRREPVR VGRVRATLFL PPGTGPFPGI LDLFGSGGGL CEYRASLLAG
HGFAVLALAY FRFEDLPEYL NNVCLEYFEE AVDFMLQHPE VKGPSVGLLG FSKGGDLCLS
MASFLKGITA TAVINACVAN TIAPLHYKDM IIPNLSSDPG KYKITESGLL NLADIWNDPL
EKPNHRSLIP LEKAQGPFLF IVGMDDHNWK SEFYAQIASE RLQAHGKDRP QIIYYPGTGH
CIDPPYFPLC RASVHAVLDQ PVFYGGEPKA HSRAQVDAWQ QIQTFFHKHL NGKKSVKPSK
L
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