ID A0A340XNN8_LIPVE Unreviewed; 801 AA.
AC A0A340XNN8;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=DENN domain-containing protein 1C {ECO:0000313|RefSeq:XP_007460635.1};
GN Name=DENND1C {ECO:0000313|RefSeq:XP_007460635.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007460635.1};
RN [1] {ECO:0000313|RefSeq:XP_007460635.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007460635.1; XM_007460573.1.
DR AlphaFoldDB; A0A340XNN8; -.
DR STRING; 118797.A0A340XNN8; -.
DR GeneID; 103081959; -.
DR KEGG; lve:103081959; -.
DR CTD; 79958; -.
DR InParanoid; A0A340XNN8; -.
DR OrthoDB; 5398783at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.450.200; -; 1.
DR Gene3D; 3.40.50.11500; -; 1.
DR Gene3D; 6.10.140.1000; -; 1.
DR InterPro; IPR001194; cDENN_dom.
DR InterPro; IPR005112; dDENN_dom.
DR InterPro; IPR043153; DENN_C.
DR InterPro; IPR040032; DENND1A/B/C.
DR InterPro; IPR037516; Tripartite_DENN.
DR InterPro; IPR005113; uDENN_dom.
DR PANTHER; PTHR13196; DENN DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR13196:SF25; DENN DOMAIN-CONTAINING PROTEIN 1C; 1.
DR Pfam; PF03455; dDENN; 1.
DR Pfam; PF02141; DENN; 1.
DR Pfam; PF03456; uDENN; 1.
DR SMART; SM00801; dDENN; 1.
DR SMART; SM00799; DENN; 1.
DR SMART; SM00800; uDENN; 1.
DR PROSITE; PS50211; DENN; 1.
PE 4: Predicted;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Reference proteome {ECO:0000313|Proteomes:UP000265300}.
FT DOMAIN 13..398
FT /note="UDENN"
FT /evidence="ECO:0000259|PROSITE:PS50211"
FT REGION 500..540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 606..785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 632..683
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 697..713
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 720..746
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 801 AA; 87523 MW; 2BB515B6B651D7D9 CRC64;
MGSTAERGLP ALFEWFFEAA YPPSLQEDPP ILRQFPPDFR DQEAMQMVPK FCFPFDVERE
PPSTAVQHFT FALTDLTGTR RFGFCRLRAG AHSCLCILSH LPWFEVFYKL LNTVGDLLAQ
DQASEVDEIL LYLLQQPLPG TQDSVGLELG SGVTISSAQG IPPPGPGKSM PFSCFVAPDS
GRLPSIPENR NLTELVVAVT DDNIVGLFAA LLAERRVLLT SRKLSTLTSC VHASCALLYP
MRWEHVLIPT LPPHLLDYCC APMPYLIGVH ASLAERVREK ALEDVVMMNV DSNTLETPFD
DVQALPPDVV SLLRLRLRKV TLAPGEGVSR LFLKAQALLF GGYRDALVCG PGQPVTFSEE
AFLAQNPGAP LQAFHRRAVH LQLFKQFIEG RLEKLNTGEG FSDLFEQEIT CSGASSGTLR
SYQLWADNLK KGGGALLHSV KAKTQPAVRN MYRSAKSGLK GVQSLLTYKD GDSGLQRGGS
LRAPSLTSRS DCLQQRLPIT QHFGQNRPLR PSRRLQREER PSESLGEGTP SLSPEDAQEP
LAEEALDGSF LGSGEELDLL SEILDSLSVR ATRNSSLRPS QSLDCCHRED LDGCLSLPDI
PRRWRWQADD KKPPGPQPLS LSVGLPPLHT PQPSDAMSSS KHPTSQLPSE ASPEIISPSQ
SSTASADPSG KGDPSSSLTE PQPLRLSPPH EATEDPTAQE SPCSQLSTAP SPRESPPLLT
PTKPNSDITW TSQVLDSFSD PGSPENPRAQ PSEVLLPERT HLQPHEEPGA PRSPDPPARN
WRGLQARSLP RVAELKKCFE G
//
