ID A0A340XRM9_LIPVE Unreviewed; 3065 AA.
AC A0A340XRM9;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=E1A-binding protein p400 {ECO:0000313|RefSeq:XP_007462857.1};
GN Name=EP400 {ECO:0000313|RefSeq:XP_007462857.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007462857.1};
RN [1] {ECO:0000313|RefSeq:XP_007462857.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007462857.1; XM_007462795.1.
DR STRING; 118797.A0A340XRM9; -.
DR GeneID; 103075755; -.
DR KEGG; lve:103075755; -.
DR CTD; 57634; -.
DR InParanoid; A0A340XRM9; -.
DR OrthoDB; 5475375at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR CDD; cd00167; SANT; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR031575; EP400_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR014012; HSA_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR46459:SF1; E1A-BINDING PROTEIN P400; 1.
DR PANTHER; PTHR46459; E1A-BINDING PROTEIN P400-RELATED; 1.
DR Pfam; PF15790; EP400_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07529; HSA; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00573; HSA; 1.
DR SMART; SM00717; SANT; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51204; HSA; 1.
DR PROSITE; PS50090; MYB_LIKE; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000265300}.
FT DOMAIN 740..812
FT /note="HSA"
FT /evidence="ECO:0000259|PROSITE:PS51204"
FT DOMAIN 1044..1209
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1838..1990
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 2300..2361
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT REGION 1..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 123..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 224..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 286..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 490..712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 940..962
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1411..1523
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2056..2080
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2219..2243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2456..2536
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2728..2778
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3025..3065
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..47
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..63
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..538
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 540..599
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 609..638
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 639..653
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1424..1438
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1459..1487
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2219..2242
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2470..2506
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2514..2535
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2737..2754
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2755..2778
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3025..3047
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3065 AA; 332404 MW; 24C0B5FAD2E185BD CRC64;
MHHGSGPQNV QHPLQRSRAF AGSEEEQQAR PNPPQSPATP FAPAASPSAP QSPGYQVQQL
MNRSPVAGQS VNIALQNVGP VVGGNPQITL APLPLPSPTS PGFQFSAQQR RFEHGSPSYI
QVTSPLSQQV QTQSPTQPSP GPGPGLQSVR AGAPGPGLGL CSSSPTGGFV DASVLVRQIS
LSPSSGGHFV FQEGSGLAQM APGAQVQLQH TGTPITVRER RLSQPHAQSG GTVHHLGPQS
PAAAGGAGLQ PLSSPGHITT TSLPPQISSI IQGQLIQQQQ VLQGPPLTRP LLPGVGGTSA
FGMTSPPPPT SPSRTAAPPG LSSLPVPSAG SAGIRKAPRK LEEIPAASQE LAQMRKQCLD
YHFREMEALK AAFKEYLVEL FFLQHLQGNM MDFLAFKKKH YAPLQAYLRQ NDLDLEEEDE
DEDEEKSEVI NDEQQALAGT LVAGAGSVIE TDPFKRQQAG PPAEQSKRPR LEVGHQGVVF
QHPGVNTGVP LQQLMPTVQG GMPPAPQAAQ LAGQKQSQQR YDPSTGPPVQ NAASLHTPPP
QLPTRLPPAG LPAAPLPPAL QFPPQPQTAE PQTPLPVPVK TQPPSAPAPA PPPGQLPAAL
HVPVPTKAQM QAPPLPSQPQ TVAPPRPPMD PAQPCPRPLP SASSASTVVP ASGSGPGPSP
ARASPVNRPS PAAKSLSPVI ARSPGAAVSA PPKPQSPAQS AAAPHDGSQD KLAAQVALEN
QIHQRIADLR KEGLWSLRRL PKLQEAPRSK SHWDYLLEEM QWMATDFAQE RRWKVAAAKK
LVRTVARHHE EKQLREERGR REEQNRLRRI AASTAREIEY FWSNIEQVVE IKLQVELEEK
RKKALNFQKV SRKGKESRPT GLDALRENFV DSGIPGRKRK ASTSLTDDEV EDEEETIAEE
EALEGAADHQ AELLELAREA ELPLIDLMKL YEGAFLPNFQ WPQPKPDSEE TSEDEDVEDC
SGDRESRKGV VLIDSLFIMD QFKATERVVV GKPHTKDIAE VTAVAEAILP KGSARISTAV
KLNAPALLYG ALRDYQKIGL DWLAKLYRKN LNGVLADEAG LGKTVQIIAF FAHLACNEGN
WGPHLVVVRG CNILRWELEL KRWCPGLKTL LYVGSRRELK AKRQGWTEPN RINVCITSYK
QFFKGYASFT RVRWKCLVID EMQRVKGMTE RHWEAVFTLQ SQQRLLLIDA PLHNTFLELW
TMVHFLIPGI SRPYLHLPLK APSEENQDYY HKVVIRLHRV TQPFILRRTK RDVEKQLTKK
YEHVLKCRLS SRQKALYEDV ILQPGTQEAL KSGRFVDVLS ILLRLQRICN HPGLVAPRLP
ESSYTAGPLQ CRSASLILKA LDRDFWKETD LSIFDLIGLE NKMTRHESEL LGKKKVTRRL
FEELFTAPPP SGRPAAIRLK PSRLFQPVQY GQKPEGRTVA FPSTHPPRTA TPTATATPQG
HVRGRPPVAT FSANPDAKAP ATPFQTSQPS TGAPRHQPAS TFSTAPSPAH PVKLRAQTTA
PASTPGPPQP QPQAPSHPAG QSALPQGLVL TSQAQARLPS GEVVKIAQLA SLAGPPSRVA
QPESPVTLQF QGNKFTLSHS QLRQLTAGQP LQLQGSVLQI VSAPGQSYLR PPGPVVMQTV
SQAGALNALG SKPPAGGPSP APMTPPVGVP SRVAVSPLAA GEPGVASKPA SPVAGPTQEE
KTRLLKERLD QIYFVNERRC SRTPVYGRDL LGVCSLPSRG QLPWLGAPDG GHGKGAGPAS
RCTSPSTTHR DLILTLTQRQ ESLQDVMDRV VCVIPPVVAA PPCLWVARPP SRYSHKMRLF
RHYLREHTAP FAQQLQRVTA LRSLRFPELR LVQFDSGKLE ALAILLQKLK SEGRRVLILS
QMVLMLDILE MFLNFHYLTY VRIDENANSE QRQDLMRSFN RDRRVFCALL STHSRATGVS
LVEADAVVFY DHDLNPVMDA KAQEWCDRIG RRKDVHIYRL VSGNSIEEKL LKNGTKDLIR
EVAAQGNDYS MAFLTQRTIQ ELFEVYPPMD DTGFPVKAEE FVVLSQEPSV TETIAPKIAR
PFIEALRSIE CLEEDAHEPA EELAPGSRRP DGSRWGEEPS PLEELADFMG QLTPIEKYAL
NYLELFHTST DQEKERNSEG AVLAAVGEWE ARHARALRER EARARREPEQ QLLTYTREDA
CRAEFVYEGA DGQTEVMPLW TPPTPPQDDN DIYIDSVMCL MYETTPIPES KLPPVYVRKE
RRRHKTDPSA AGRKKKQRHG EAVVPPRSLF DRAAPAMLKA RREGKEQRKN ILLKQQAQFA
KPLPAFAKPA AESGPDSPEW LISEDWALLQ AVKQLLELPL NLTVVSPAHT PNWDLVSDVV
NSCSRIYRSS KQCRNRYENV LIPREEGKSK NNRPLRTGQM YAQDENATHT QLYTSHFDLM
KMTAGKRSPP IKPLLGMNPF QKNPKHASVL AESGINYDKP LPPIQVASLR AERIAKEKKA
LADQQKAQQP PVAQPPPPPP PPQPQPPPPQ QPPPPLPQPP SAGSQQPAGP PAVQPQAQAQ
PPAQPTPPPP KVPPAITTVG SAAVLAGAIK TSVTGTSMPT GTVSGNVIVN TIAGVPAATF
QSINKRLASP VAPGALTTSG GSAPAQVVHT QPRAVGSPAT ATSDMVSLAP TQGVRAVTSV
TASAVVTTSL TPVQTPTRSL VTQVSQATGV QLPGKTITPA HFQLLRQQQQ QQQASQVQVP
QIQGQAQAPA QIKAVGKLTP EHLIKMQKQK LQLPQQAPPA QAPPGPPQPT AQVQVQPPQP
TQQQSPQLTT VTAPRPGALL TGTTVANLQV ARLTRVPTSQ LQAQGQMQAP APQPAQVALA
KPPVVSVPAA VVSSPGVTTL PMNVAGISVA IGQPQKAAGQ TVVAQPVHVQ QLLKLKQQAV
QQQKAIQPQA APGPAAVQQK ITAQQIAAQG QPQKVTYATQ PALKTQFLTT PISQAQKLAG
TQQVQTQIQV AKLPQVVQQQ TPVASIQQVA SASQQASPQT VTLTQATAAG QQVQVIPAVT
ATAQVVQQKL MQQQVVTTAA AQLQTPGVPN PAQVPASSDS PNQQPKLQMR VPAVRLKTPT
KPPCP
//
