ID   A0A340XWW0_LIPVE        Unreviewed;       310 AA.
AC   A0A340XWW0;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Syndecan {ECO:0000256|RuleBase:RU000649};
GN   Name=SDC1 {ECO:0000313|RefSeq:XP_007463809.1};
OS   Lipotes vexillifer (Yangtze river dolphin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Lipotidae; Lipotes.
OX   NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007463809.1};
RN   [1] {ECO:0000313|RefSeq:XP_007463809.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- FUNCTION: Cell surface proteoglycan. {ECO:0000256|RuleBase:RU000649}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479,
CC       ECO:0000256|RuleBase:RU000649}; Single-pass type I membrane protein
CC       {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU000649}.
CC       Secreted, extracellular exosome {ECO:0000256|ARBA:ARBA00004550}.
CC   -!- SIMILARITY: Belongs to the syndecan proteoglycan family.
CC       {ECO:0000256|ARBA:ARBA00005343, ECO:0000256|RuleBase:RU000649}.
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DR   RefSeq; XP_007463809.1; XM_007463747.1.
DR   AlphaFoldDB; A0A340XWW0; -.
DR   STRING; 118797.A0A340XWW0; -.
DR   GeneID; 103071864; -.
DR   KEGG; lve:103071864; -.
DR   CTD; 6382; -.
DR   InParanoid; A0A340XWW0; -.
DR   OrthoDB; 5360052at2759; -.
DR   Proteomes; UP000265300; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR003585; Neurexin-like.
DR   InterPro; IPR001050; Syndecan.
DR   InterPro; IPR027789; Syndecan/Neurexin_dom.
DR   InterPro; IPR030479; Syndecan_CS.
DR   PANTHER; PTHR10915; SYNDECAN; 1.
DR   PANTHER; PTHR10915:SF5; SYNDECAN-1; 1.
DR   Pfam; PF01034; Syndecan; 1.
DR   SMART; SM00294; 4.1m; 1.
DR   PROSITE; PS00964; SYNDECAN; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180,
KW   ECO:0000256|RuleBase:RU000649};
KW   Heparan sulfate {ECO:0000256|ARBA:ARBA00023207,
KW   ECO:0000256|RuleBase:RU000649};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Proteoglycan {ECO:0000256|ARBA:ARBA00022974,
KW   ECO:0000256|RuleBase:RU000649};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265300};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000649};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..310
FT                   /note="Syndecan"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5016383875"
FT   TRANSMEM        252..276
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          275..293
FT                   /note="Neurexin/syndecan/glycophorin C"
FT                   /evidence="ECO:0000259|SMART:SM00294"
FT   REGION          27..243
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          283..310
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        52..70
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        78..96
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        121..151
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        212..226
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   310 AA;  32401 MW;  989AE92A894F32C0 CRC64;
     MRRPALWLWL CALALRLQPA LPQTVAVNVP PEDQDGSGDD SDSFSGSGAG ALPDITLSQQ
     TPSTWKDKGL LTATPTAPEP SRPDTMVTST SILPTGEQPE EGGLVLLGEL GPGLTPQEKE
     ATHPPSGTTL HPTTHRASTA RATTAQGPAT SHPHRDVQPD HHETSAPTGH GQLDPQAPSV
     EDGGSAATEK AAEDEAPTQL PEGEGSGEQD FTFDVSAENS AGATVEPEQW NVPPGDPGAR
     GASQGFLDRK EVLGGVVAGG LVGLIFAVCL VGFMLYRMKK KDEGSYSLEE PKQANGGAYQ
     KPSKQEEFYA
//