ID A0A340Y7D2_LIPVE Unreviewed; 627 AA.
AC A0A340Y7D2;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Netrin-4 isoform X2 {ECO:0000313|RefSeq:XP_007468282.1};
GN Name=NTN4 {ECO:0000313|RefSeq:XP_007468282.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007468282.1};
RN [1] {ECO:0000313|RefSeq:XP_007468282.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_007468282.1; XM_007468220.1.
DR AlphaFoldDB; A0A340Y7D2; -.
DR GeneID; 103074281; -.
DR CTD; 59277; -.
DR OrthoDB; 2916807at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR CDD; cd00055; EGF_Lam; 3.
DR CDD; cd03578; NTR_netrin-4_like; 1.
DR Gene3D; 2.40.50.120; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 1.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR InterPro; IPR035811; Netrin-4_NTR.
DR InterPro; IPR001134; Netrin_domain.
DR InterPro; IPR018933; Netrin_module_non-TIMP.
DR InterPro; IPR008993; TIMP-like_OB-fold.
DR PANTHER; PTHR10574:SF282; NETRIN-4; 1.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR Pfam; PF00053; Laminin_EGF; 3.
DR Pfam; PF00055; Laminin_N; 1.
DR Pfam; PF01759; NTR; 1.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00643; C345C; 1.
DR SMART; SM00180; EGF_Lam; 3.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR SUPFAM; SSF50242; TIMP-like; 1.
DR PROSITE; PS01248; EGF_LAM_1; 1.
DR PROSITE; PS50027; EGF_LAM_2; 2.
DR PROSITE; PS51117; LAMININ_NTER; 1.
DR PROSITE; PS50189; NTR; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460};
KW Reference proteome {ECO:0000313|Proteomes:UP000265300};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..627
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016327956"
FT DOMAIN 30..261
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 332..394
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 395..448
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 505..626
FT /note="NTR"
FT /evidence="ECO:0000259|PROSITE:PS50189"
FT DISULFID 362..371
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 422..431
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
SQ SEQUENCE 627 AA; 69811 MW; 96067BF26908DD5F CRC64;
MGSCARLLLL WGCSAVAAGL SGVAGVSSRC EKACNPRMGN LALGRKLWAD TTCGQNATEL
YCFYSENTDL TCQQPKCDKC SAAQPHLAHL PAAMADSSFR FPRTWWQSAE DVHREKIQLD
LEAEFYFTHL IMVFKSPRPA AMVLDRSQDF GKTWKPYKYF ATNCTATFGL EDDVVKKGAI
CTSRYSNPFP CTGGEVIFRA LSPPYDVENP YSAKVQEQLK ITNLRVQLLK RQSCPCQRNN
LNAKPQHFTH YAIYDFIVKG SCFCNGHADQ CIPVDGFRPV KAPGAFHVVH GKCMCKHNTA
GTHCQHCAPL YNDRPWEAAD GKTGSPKECR TCKCNGHADA CHFDINVWEA SGNRSGGVCN
DCQHNTEGQH CQRCKPGFYR DLRRPFSAPD ACKLCSCHPV GSAVLPFSSV TFCDPSDGDC
PCKPGVAGPH CDRCMVGYWG FGAYGCRPCD CAGSCDPLTG DCISSTDIDW HHEIPNFHSM
HNKSEPTWEW EDEQGFSALR HSGKCECKEQ VLRNSKAFCG MKYSYVLKIK ILSAHDKGSH
AEVNVKIKKV LKSTKLKILR GKRTLYPESW TNRGCTCPIL NPGLEYLVAG HEDVRTGKLV
VNMKSFVQHW KPSLGRKVMD ILKRECK
//
