ID A0A340YCH6_LIPVE Unreviewed; 375 AA.
AC A0A340YCH6;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=E3 ubiquitin-protein ligase RNF133 {ECO:0000313|RefSeq:XP_007471376.1};
GN Name=RNF133 {ECO:0000313|RefSeq:XP_007471376.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007471376.1};
RN [1] {ECO:0000313|RefSeq:XP_007471376.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007471376.1; XM_007471314.1.
DR AlphaFoldDB; A0A340YCH6; -.
DR STRING; 118797.A0A340YCH6; -.
DR GeneID; 103090904; -.
DR KEGG; lve:103090904; -.
DR CTD; 168433; -.
DR InParanoid; A0A340YCH6; -.
DR OrthoDB; 5474929at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd02122; PA_GRAIL_like; 1.
DR CDD; cd16802; RING-H2_RNF128-like; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46539; E3 UBIQUITIN-PROTEIN LIGASE ATL42; 1.
DR PANTHER; PTHR46539:SF2; RING FINGER PROTEIN 150 ISOFORM X1; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000265300};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT SIGNAL 1..34
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 35..375
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016460749"
FT TRANSMEM 190..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 256..297
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 332..375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 351..366
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 375 AA; 41726 MW; 8F8C2F5A68E4E871 CRC64;
MRLLKIGTRR NNSASSWLMK FSFLWLLSQH CCRASAVWTA YTNISFHVGS RMLSELGETG
VFGRSSALKR VAGVIVPPEG KTQNACNPST SFNTSKNSET WLALVARGGC TFTQKIKVAV
EKGASGVIIY NFLGTGNQVF PMSHQAFEDI VVVMIGNLKG MEILHLIQKG VHVTVMIEVG
RKHIIWMNHY FVSFVIVTTA TLACFIFYHI QRLWVARIQN RRWQRLTTDL KKACGQLQLR
VLKEGDKEVS PNGDSCVVCF ELYKPDDTVR ILTCKHFFHK NCIDPWILAH GTCPMCKCDI
LKALGIQVDV EDGTESLQVL ILNEMPGILS PPEEGINNAL PPVGRSNKVT HAEEYPTSQN
DGPSNSVAAD VHRPP
//
