ID A0A340YEY4_LIPVE Unreviewed; 681 AA.
AC A0A340YEY4;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Ligand of Numb protein X 2 {ECO:0000313|RefSeq:XP_007471508.1};
GN Name=LNX2 {ECO:0000313|RefSeq:XP_007471508.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007471508.1};
RN [1] {ECO:0000313|RefSeq:XP_007471508.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007471508.1; XM_007471446.1.
DR AlphaFoldDB; A0A340YEY4; -.
DR STRING; 118797.A0A340YEY4; -.
DR GeneID; 103081842; -.
DR KEGG; lve:103081842; -.
DR CTD; 222484; -.
DR InParanoid; A0A340YEY4; -.
DR OrthoDB; 3028121at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16780; mRING-HC-C3HC3D_LNX2; 1.
DR CDD; cd00992; PDZ_signaling; 4.
DR Gene3D; 2.30.42.10; -; 4.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR19964:SF33; LIGAND OF NUMB PROTEIN X 2; 1.
DR PANTHER; PTHR19964; MULTIPLE PDZ DOMAIN PROTEIN; 1.
DR Pfam; PF00595; PDZ; 4.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00228; PDZ; 4.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 4.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50106; PDZ; 4.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000265300};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 50..88
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 226..311
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 332..415
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 459..545
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 591..673
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 179..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 412..445
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..439
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 681 AA; 74363 MW; 4F8320140E78983C CRC64;
MGTTNDEMVS VEQTSSSSFN PLCFECGQQH WTRENHLYNY QDEVDDDLVC HICLQPLLQP
LDTPCGHTFC CKCLRNFLQE KDFCPLDRKR LHFKLCKKSS ILVHKLLDKL LVLCPFSSVC
QDVVQRCDLE AHLKNRCPGA SHQRVALERR KTSKAQTEIE NENGTTVIDL PATLSPEADC
SGPTLTSASL PAWTEEPGLD NPAFEESPTG DTTQQPLSLP EGEITTIEIH RSNPYIQLGI
SIVGGNETPL INIVIQEVYR DGIIARDGRL LAGDQILQVN HHNISSVSHN HARAVLSQPC
STLHLTVLRE RRCGGRAHSR PVGGSPPEEV FQVVLHKRDS AEQLGIKLVR RTDEPGVFVL
DLLEGGLAAQ DGRLSGNDRV LAVNGHDLKH GTPELAAQII QASGERVNLT IARPGKPQPG
NAVREAGTQS SQHHAQPLPY NRPSSHKDLA QCVTCQEKHI TVKKEPHESL GMTVAGGRGS
KSGELPIFVT SVPPHGCLAR DGRIKRGDIL LNINGIDLTS LSHSEAVAML KASATSPTVA
LKALEVQVVE EAAHGPDEQP STVSENEYDA SWSPSWVMWL GLPSALHSCH DIVLRRSYLG
SWGFSIVGGY EENHTNQPFF IKTIVLGTPA YYDGRLKCGD MIVAVNGLST VGMSHSALVP
MLKGQRNKVT LTVVCWPGSL V
//
