ID A0A340YFQ4_LIPVE Unreviewed; 710 AA.
AC A0A340YFQ4;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Dynein regulatory complex protein 1 {ECO:0000256|ARBA:ARBA00013815};
DE AltName: Full=Coiled-coil domain-containing protein 164 {ECO:0000256|ARBA:ARBA00031554};
GN Name=DRC1 {ECO:0000313|RefSeq:XP_007470864.1};
OS Lipotes vexillifer (Yangtze river dolphin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Lipotidae; Lipotes.
OX NCBI_TaxID=118797 {ECO:0000313|Proteomes:UP000265300, ECO:0000313|RefSeq:XP_007470864.1};
RN [1] {ECO:0000313|RefSeq:XP_007470864.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC {ECO:0000256|ARBA:ARBA00004430}. Cytoplasm, cytoskeleton, flagellum
CC axoneme {ECO:0000256|ARBA:ARBA00004611}.
CC -!- SIMILARITY: Belongs to the DRC1 family.
CC {ECO:0000256|ARBA:ARBA00009688}.
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DR RefSeq; XP_007470864.1; XM_007470802.1.
DR AlphaFoldDB; A0A340YFQ4; -.
DR GeneID; 103087892; -.
DR CTD; 92749; -.
DR OrthoDB; 5476746at2759; -.
DR Proteomes; UP000265300; Unplaced.
DR GO; GO:0005858; C:axonemal dynein complex; IEA:InterPro.
DR GO; GO:0031514; C:motile cilium; IEA:UniProtKB-KW.
DR GO; GO:0070286; P:axonemal dynein complex assembly; IEA:InterPro.
DR InterPro; IPR039505; DRC1/2_N.
DR InterPro; IPR039750; DRC1/DRC2.
DR InterPro; IPR029440; DRC1_C.
DR PANTHER; PTHR21625:SF1; DYNEIN REGULATORY COMPLEX PROTEIN 1; 1.
DR PANTHER; PTHR21625; NYD-SP28 PROTEIN; 1.
DR Pfam; PF14772; NYD-SP28; 1.
DR Pfam; PF14775; NYD-SP28_assoc; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Flagellum {ECO:0000256|ARBA:ARBA00022846};
KW Reference proteome {ECO:0000313|Proteomes:UP000265300}.
FT DOMAIN 98..199
FT /note="Dynein regulatory complex protein 1/2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14772"
FT DOMAIN 630..689
FT /note="Dynein regulatory complex protein 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14775"
FT REGION 560..589
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 102..139
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 167..234
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 280..314
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 344..378
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 664..694
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 710 AA; 83302 MW; 979CA690E23AB280 CRC64;
MNPPGSLRVL EEKEKEHLAT PTVGPSIHSD IPQERIQARR LRIAARLEAR RREALGEYLD
GKESEEDQSK SYRQKEESRL KLAKLLLCGT ELVTNIQVAA DIREVHRRVE EEEIKRQRLE
KLENEVKTSQ DKFDEITVKW EEGKQKRIPQ DLWEMLNAQQ VHCAGLIEDK NKLISELQQE
LETKHDQYVK DLKKQSGDIC LLLERMEEQV KNVMKAFRQE LQHIENAFEV ERQELLTSNK
KKWEQALQAH NAKEMEYLTH RIKKVEDHEK QLNKQRIWDC EEYNTIKIKL EQDVQILEQQ
LQQMKATYQL NQEKLEYNFQ VLKKRDEEST VIKSQQKSKI NCLHDVLNNL RSKYNKQVKQ
FQEENQSLTS DYKRLVTQFK EMQKAIRHFA LIDDKQFREI WLMNEEEAKD LISRAFDVDR
VIHTHHLGLP WTAPDFWFLK NVGPISQQQR KSATQILEEV LMEAEEEGAE EAASEPGSYL
DLPKQVSAKT TRKILMLLCD ESGFLIESKL LSLLLPLDKN ECYLLKLDAI FSALGIENED
DLYKLVDFFL RYQAHHSAPS QKLDLQGEKE GSLVEREPQE KQPPPSPRLI HPNDVLKILE
AFVTGLRKPR DFRAPVKLLK VVRDDSKDSE YWKALTTVIP ATTLNLWDAL YTALEKYHLV
LTQRAKLLIE NSSLERQNTE LQQLLQQYVD SKINSELQVP PTQVFRVPTK
//
