ID A0A341BMW3_NEOAA Unreviewed; 592 AA.
AC A0A341BMW3;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Transcriptional repressor p66-beta isoform X2 {ECO:0000313|RefSeq:XP_024604095.1};
GN Name=GATAD2B {ECO:0000313|RefSeq:XP_024604095.1};
OS Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)
OS (Neophocaena phocaenoides subsp. asiaeorientalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Phocoenidae; Neophocaena.
OX NCBI_TaxID=1706337 {ECO:0000313|Proteomes:UP000252040, ECO:0000313|RefSeq:XP_024604095.1};
RN [1] {ECO:0000313|RefSeq:XP_024604095.1}
RP IDENTIFICATION.
RC TISSUE=Meat {ECO:0000313|RefSeq:XP_024604095.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_024604095.1; XM_024748327.1.
DR AlphaFoldDB; A0A341BMW3; -.
DR Proteomes; UP000252040; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 6.10.250.1650; -; 1.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR InterPro; IPR040386; P66.
DR InterPro; IPR032346; P66_CC.
DR InterPro; IPR000679; Znf_GATA.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR13455:SF4; TRANSCRIPTIONAL REPRESSOR P66-BETA; 1.
DR PANTHER; PTHR13455; TRANSCRIPTIONAL REPRESSOR P66-RELATED; 1.
DR Pfam; PF00320; GATA; 1.
DR Pfam; PF16563; P66_CC; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR PROSITE; PS50114; GATA_ZN_FINGER_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00094}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000252040};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-ProRule:PRU00094};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00094}.
FT DOMAIN 413..443
FT /note="GATA-type"
FT /evidence="ECO:0000259|PROSITE:PS50114"
FT REGION 62..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 159..186
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 79..118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 592 AA; 65164 MW; 3D1627E487D11185 CRC64;
MDRMTEDALR LNLLKRSLDP ADERDDVLAK RLKMEGHEAM ERLKMLALLK RKDLANLEVP
HELPTKQDGS GVKGYEEKLN GNLRPHGDNR TAGRPGKENI NDEPVDMSAR RSEPDRGRLT
PSPDIIVLSD NEASSPRSSS RMEERLKAAN LEMFKGKGIE ERQQLIKQLR DELRLEEARL
VLLKKLRQSQ LQKENVVQKT PVVQNAASIV QPSPAHVGQQ GLSKLPSRPG AQGVEQNLRT
LQGHSVIRSA TNTTLPHMLM SQRVIAPNPA QLQGQRGPPK PGLVRTTTPN MNPAINYQPQ
SSSSVPCQRT TSSAIYMNLA SHIQPGTVNR VSSPLPSPSA MTDAANSQAA AKLALRKQLE
KTLLEIPPPK PPAPLLHFLP SAANSEFIYM VGLEEVVQSV IDSQGKSCAS LLRVEPFVCA
QCRTDFTPHW KQEKNGKILC EQCMTSNQKK ALKAEHTNRL KNAFVKALQQ EQEIEQRLQQ
QAALSPTTAP AVSSVSKQET IMRHHTLRQA PQPQSSLQRG IPTSARSMLS NFAQAPQLSV
PGGLLGMPGV NIAYLNTGIG GHKAPSLADR QREYLLDMIP PRSISQSISG QK
//
