ID A0A344L092_9PSEU Unreviewed; 314 AA.
AC A0A344L092;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Hydroxymethylglutaryl-CoA lyase {ECO:0000313|EMBL:AXB41466.1};
GN ORFNames=A4R43_02110 {ECO:0000313|EMBL:AXB41466.1};
OS Amycolatopsis albispora.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis.
OX NCBI_TaxID=1804986 {ECO:0000313|EMBL:AXB41466.1, ECO:0000313|Proteomes:UP000250434};
RN [1] {ECO:0000313|EMBL:AXB41466.1, ECO:0000313|Proteomes:UP000250434}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WP1 {ECO:0000313|EMBL:AXB41466.1,
RC ECO:0000313|Proteomes:UP000250434};
RA Wang H., Chen S., Wu Q.;
RT "Complete genome sequence and analysis of deep-sea sediment isolate,
RT Amycolatopsis sp. WP1.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the HMG-CoA lyase family.
CC {ECO:0000256|ARBA:ARBA00009405}.
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DR EMBL; CP015163; AXB41466.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A344L092; -.
DR KEGG; aab:A4R43_02110; -.
DR OrthoDB; 9784013at2; -.
DR Proteomes; UP000250434; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016833; F:oxo-acid-lyase activity; IEA:InterPro.
DR CDD; cd07938; DRE_TIM_HMGL; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR043594; HMGL.
DR InterPro; IPR000891; PYR_CT.
DR PANTHER; PTHR42738; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR PANTHER; PTHR42738:SF7; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:AXB41466.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 12..280
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
SQ SEQUENCE 314 AA; 32525 MW; 2525D965FADA0123 CRC64;
MNRGSRKTEI DVLVSEVGPR DGLQSVDRTM PTAVKQRWIT ALAGSGLREI EVGSFVSPKR
LPQLADTADV VAHALTIPDL TVLALVPNLV GARNAVAAGT RALTMPLSAS RAHSQNNIGM
TPEQALEQVG LVCELKAATP GLSVEVGIST AFGCTLEGPV DEDWVIELAV RAAGRGADSV
GLSDTTGYAN PAQVRRLFTR LRAELGDRAG GAHLHNTRGQ GLANVVAALD AGVTTFDSSQ
GGLGGCPYAP GASGNIVTED LVFLLESMGL RTGVDIEALV AARTIIGDGL PGEQLYGHVP
DAGLTKGFQY AKVD
//
