ID   A0A344LBI0_9PSEU        Unreviewed;       682 AA.
AC   A0A344LBI0;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=Membrane transport protein MMPL domain-containing protein {ECO:0000259|Pfam:PF03176};
GN   ORFNames=A4R43_25355 {ECO:0000313|EMBL:AXB45404.1};
OS   Amycolatopsis albispora.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Amycolatopsis.
OX   NCBI_TaxID=1804986 {ECO:0000313|EMBL:AXB45404.1, ECO:0000313|Proteomes:UP000250434};
RN   [1] {ECO:0000313|EMBL:AXB45404.1, ECO:0000313|Proteomes:UP000250434}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WP1 {ECO:0000313|EMBL:AXB45404.1,
RC   ECO:0000313|Proteomes:UP000250434};
RA   Wang H., Chen S., Wu Q.;
RT   "Complete genome sequence and analysis of deep-sea sediment isolate,
RT   Amycolatopsis sp. WP1.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CP015163; AXB45404.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A344LBI0; -.
DR   KEGG; aab:A4R43_25355; -.
DR   Proteomes; UP000250434; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR004869; MMPL_dom.
DR   PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR   PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR   Pfam; PF03176; MMPL; 2.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        169..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        194..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        220..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        260..287
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        293..321
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        342..366
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        490..509
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        516..540
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        560..581
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        602..623
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        635..658
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          85..352
FT                   /note="Membrane transport protein MMPL"
FT                   /evidence="ECO:0000259|Pfam:PF03176"
FT   DOMAIN          414..665
FT                   /note="Membrane transport protein MMPL"
FT                   /evidence="ECO:0000259|Pfam:PF03176"
SQ   SEQUENCE   682 AA;  71328 MW;  8DBBA27D073BC7AF CRC64;
     MTVRRIARWS ATHPWQAIVG WLAFVAIAFA AGTLTGTNQA RGEDFWIGEA GRAEQMAAEG
     GISRPPVENV LITPASEPAA AEVAHRVRDL PGVADVGEPV RSPDGGSLLV VITMAGDDQQ
     AGEHVEPVIE QTGAVAAAHP EIRLVQTGDA SQERGLGAQL GQGVLITKAI TLPVTLLILF
     LVFGSLLAAG IPLLLALTAI LGSLGLYALA SAFFPDAGGA VTSILLMMGM AVGVDYSLFA
     LKRVREERDR SRGQLSHAAA VEIAAATSGR AIVVSGLAVI VSLAGLYLAT DVIFSSIATG
     TIIVVAVAVL SAVTVLPALL AKLGPRLETT RRPRPPRLWN RLLRPAVEHP VPTLLVGLLL
     IGALAIPGLN MKLGVEGINT FPRSVPEIAA YDELVAAFPD RGASHMVVVR GDNAAQVAAD
     LATPDARVVS SVDGRTQRVE LPIPYSAGTP EADDSLAQLR AQPVPPGVEL AVSGEPARGV
     DYSAHQAERL PWVVGFVLLA TFAMMALAFR SVVIGALGLV LNLLSVLAAW GALVVVFQGN
     WAEDLLGFTS TGFIGSRTPL MLFAILFGLS MDYQIFVVSR IREAVARGLP TREAVVDGIT
     GSARVVSSAA LVMVSVFLGF MFIDRIEMKQ IGLGLALAVL LDAVVVRILL LPAALSLLGK
     ASWWPGRVPE QAPPLRTPAG RA
//