ID A0A344PN07_9RHOB Unreviewed; 896 AA.
AC A0A344PN07;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=DRW48_14705 {ECO:0000313|EMBL:AXC50762.1};
OS Paracoccus suum.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Paracoccus.
OX NCBI_TaxID=2259340 {ECO:0000313|EMBL:AXC50762.1, ECO:0000313|Proteomes:UP000252023};
RN [1] {ECO:0000313|Proteomes:UP000252023}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC2-6 {ECO:0000313|Proteomes:UP000252023};
RA Heo J., Kim S.-J., Kwon S.-W.;
RT "Genome sequencing of Paracoccus sp. SC2-6.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP030918; AXC50762.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A344PN07; -.
DR KEGG; pars:DRW48_14705; -.
DR OrthoDB; 9806130at2; -.
DR Proteomes; UP000252023; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd01987; USP_OKCHK; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.20.120.620; Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038318; KdpD_sf.
DR InterPro; IPR025201; KdpD_TM.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13493; DUF4118; 1.
DR Pfam; PF13492; GAF_3; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF02702; KdpD; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:AXC50762.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000252023};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 419..441
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 448..467
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 479..498
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 676..891
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 896 AA; 96652 MW; 3BD2C91B96577BF7 CRC64;
MIPEEDRPDP ESFLAEARAE CIPARGKLKI FLGAAPGVGK TFAMLEEARA RAAAGTDVLV
GIAETHGRAE TAAILAHLEQ VPRRIIPYRG KQLSEMDLDA ILARRPQVVL IDELAHSNIP
SARHPKRWQD VEEVLEAGID VYSTLNIQHI ESLNDVVAGI TGIRVQETVP DAVLQDADDI
KVIDLSAEDL IQRMREGKVY MPAQAGRALM NFFTKPNLTA LRELALRTAA SRIDAEMLDM
ARSSGRRASA QGRLMVCLDD PATARTLVRM GRRMTDRARI PWIVATVITP GVEREGPGGN
GNMVGALELA ERLGADTLTL RAESDPAAEF LAAAERLGVT RLIVARHRRR SFLGGMLSWI
RPSVSEVLID RAEQFELTVL SPAPEGKGEA AAPGPKLQGW PRLLAEGLGA AAVSTLIAWP
FYALVPVASL AVVYLVGVLF VGVRRGTLGA IIASGISFMA YNYFFTIPFY SLRVSQYESV
VALMVFTISA LFTGSLAGRL KRQVEFMRVS QARTGTLYDF ARRIASASTT DQVLAAAAEH
IAQSVDCQSL ILMPDNGGIL QRVRSYPDLS GALEPQAFAA ALWAFQRNEP AGSGTGTLPS
SPWLFLPLAM QSRPIGVIGA KFADPQRRLD PETRRVLEAV EDQVAVAVSR IMVEGDLERA
RLATETEKLR AALLNSVSHD LRTPLVTVIG ALTAMADGTL QPAQNADLTT TALDEARRLD
RFVGNLLNMT RLGHGKLLAR REISRLTDIV GRVRADLARP LQNFDLRLDL PADLPPVLID
PVLIGQALTN LVENATKYAP DGTAIYIYGQ ADEAVVHLTV EDEGPGIPPA ERRRVFEMFH
RAVTGDGAPA GTGLGLAIAK GMVEANDGTI AVVDPQFGPG AAIRMTFAAA EGEDDG
//
