ID   A0A344U7H4_9ACTN        Unreviewed;       963 AA.
AC   A0A344U7H4;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=FAD-binding oxidoreductase {ECO:0000313|EMBL:AXE26845.1};
GN   ORFNames=C0216_28495 {ECO:0000313|EMBL:AXE26845.1};
OS   Streptomyces globosus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=68209 {ECO:0000313|EMBL:AXE26845.1, ECO:0000313|Proteomes:UP000252004};
RN   [1] {ECO:0000313|EMBL:AXE26845.1, ECO:0000313|Proteomes:UP000252004}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LZH-48 {ECO:0000313|EMBL:AXE26845.1,
RC   ECO:0000313|Proteomes:UP000252004};
RA   Ran K., Li Z., Wei S., Dong R.;
RT   "Draft genome Sequence of streptomyces globosus LZH-48.";
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR   EMBL; CP030862; AXE26845.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A344U7H4; -.
DR   KEGG; sgz:C0216_28495; -.
DR   OrthoDB; 9770306at2; -.
DR   Proteomes; UP000252004; Chromosome.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.465.10; -; 1.
DR   Gene3D; 3.30.70.2740; -; 1.
DR   Gene3D; 3.30.43.10; Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2; 1.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR004017; Cys_rich_dom.
DR   InterPro; IPR004113; FAD-bd_oxidored_4_C.
DR   InterPro; IPR016166; FAD-bd_PCMH.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016167; FAD-bd_PCMH_sub1.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR   InterPro; IPR006094; Oxid_FAD_bind_N.
DR   PANTHER; PTHR11748:SF119; D-2-HYDROXYGLUTARATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR11748; D-LACTATE DEHYDROGENASE; 1.
DR   Pfam; PF02754; CCG; 1.
DR   Pfam; PF02913; FAD-oxidase_C; 1.
DR   Pfam; PF01565; FAD_binding_4; 1.
DR   Pfam; PF13183; Fer4_8; 1.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR   SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 1.
DR   PROSITE; PS51387; FAD_PCMH; 1.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000252004}.
FT   DOMAIN          74..294
FT                   /note="FAD-binding PCMH-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51387"
FT   REGION          17..45
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   963 AA;  100199 MW;  07F24508A512DC92 CRC64;
     MSAGIWISAT GGAYPVADRP SEARPPGETS AARWKGEGVS DSGDLERTLR DALRGEVDFG
     AAARALVTMD ASNYRRVPLG VVAPRDTADV SAALRICADA GVPVVPRGGG TSIAGQATGT
     GVVLDLTRHM DALVSLDPAA RTAVVRPGLV LDRLREAVRP HGLAFGPDPS TRSRCTLGGM
     IGNNACGAHS VAWGTTADNV AELEVVAYGG AVHRIGTGWA GAPPGLRELV AGSLEVLRTG
     MAAPAGAPFT RRISGYGGLD ALLPERGAQV ARAFCGSEGT LGVVTEAVVR LVEAPRAPAL
     AVLGYAGEGA AADAAAGLLP YGPLTVEGMA EDLVPGAAGA GLLPRGAAWL FAEMPDEAAA
     RRLARTADAL DTLVVADPAG QRALWRIRED AAGTATLLPG GGLAWPGWED CAVPPARLGA
     YLRDFRALLA AHGLRGTPYG HFGEGCVHVR IGFDLVSREG VARFRAFSGE LADLVVAHGG
     SLSGEHGDGQ ARAELLPRMY GPRVIDLFGR YKDVWDPHRG MNPGILVRPA RLDENLRFEV
     LPRTGLAAEV ARCVGVARCR SADPGAAGVM CPSYRVTGEE RHSTRGRARL LHEMLAGELL
     PDGWRSAEVA EALDLCLGCK GCRSDCPVGV DMAAYKAEFL DRHWAGRIRP LAHYTLGGLP
     AWLRVLAALR LARPAGALAG LPGAARLAGL EPGRRLPGPA ARTFTRWWRG RGPSGGAGEG
     VLLWPDTFTE YLAPQAGRAA VAVLEAAGLR VGVPPGRVCC GLTYVSTGRL DRARAVLRRT
     LDAVGPVRGP VVVLEPSCAA ALRADLPALL PGDPRAARLA AAVRTFAEAL QEYAPHWRPP
     RVDRPAVGQT HCHQHAVLGD AADRRLRALA GLEGGLSGGC CGLAGNFGFE RGHLEVSRAC
     AEEQLLPSLR AAPPGAVVLA DGFSCRTQIA GLGGGVRARH LAEVLAGALP ERNPAQERPE
     RPL
//