ID   A0A345DBY6_9BURK        Unreviewed;       604 AA.
AC   A0A345DBY6;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE            EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN   Name=recQ {ECO:0000313|EMBL:AXF85874.1};
GN   ORFNames=DTO96_101614 {ECO:0000313|EMBL:AXF85874.1};
OS   Ephemeroptericola cinctiostellae.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ephemeroptericola.
OX   NCBI_TaxID=2268024 {ECO:0000313|EMBL:AXF85874.1, ECO:0000313|Proteomes:UP000252182};
RN   [1] {ECO:0000313|Proteomes:UP000252182}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F02 {ECO:0000313|Proteomes:UP000252182};
RA   Kim H.;
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|ARBA:ARBA00001665};
CC   -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC       {ECO:0000256|ARBA:ARBA00005446}.
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DR   EMBL; CP031124; AXF85874.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A345DBY6; -.
DR   KEGG; hyf:DTO96_101614; -.
DR   OrthoDB; 9760034at2; -.
DR   Proteomes; UP000252182; Chromosome.
DR   GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   GO; GO:0009432; P:SOS response; IEA:InterPro.
DR   CDD; cd17920; DEXHc_RecQ; 1.
DR   CDD; cd18794; SF2_C_RecQ; 1.
DR   Gene3D; 1.10.150.80; HRDC domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR   InterPro; IPR006293; DNA_helicase_ATP-dep_RecQ_bac.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR010997; HRDC-like_sf.
DR   InterPro; IPR002121; HRDC_dom.
DR   InterPro; IPR044876; HRDC_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR032284; RecQ_Zn-bd.
DR   InterPro; IPR018982; RQC_domain.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   NCBIfam; TIGR01389; recQ; 1.
DR   NCBIfam; TIGR00614; recQ_fam; 1.
DR   PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR   PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF00570; HRDC; 1.
DR   Pfam; PF16124; RecQ_Zn_bind; 1.
DR   Pfam; PF09382; RQC; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SMART; SM00341; HRDC; 1.
DR   SMART; SM00956; RQC; 1.
DR   SUPFAM; SSF47819; HRDC-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS50967; HRDC; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:AXF85874.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:AXF85874.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000252182}.
FT   DOMAIN          27..195
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          216..366
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   DOMAIN          530..604
FT                   /note="HRDC"
FT                   /evidence="ECO:0000259|PROSITE:PS50967"
SQ   SEQUENCE   604 AA;  67244 MW;  8323D3226DFC9AD0 CRC64;
     MPPLTALSVL QTTFGYPAFR GHQGDIIQNI IDGHDALVLM PTGAGKSLCY QIPAIVRRGV
     GVVVSPLIAL MQDQVDALNE LGVKAAFLNS TQDYETAQDV ERQLRAGALD LLYVAPERLL
     MPRTLDLLQS LDIALFAIDE AHCVSQWGHD FRPEYIKLSV LHEQFPSVPR VALTATADPQ
     TRAEIALRLQ LTEAREFVSS FDRPNIRYTI VEKNNGRAQL LNYLKAEHAG DAGIVYCLSR
     KKVEETADFL SKNGIPALPY HAGLDISVRA ANQARFLRED NLVMTATIAF GMGIDKPNVR
     FVAHLDLPKS IEGYYQETGR AGRDGAPANA WMAYGLQDVV QQRRMIAESE AGDDFKRVQY
     AKLDAMIGLC ETITCRRVQL LHYFDQSSEP CGNCDTCLHP PKAVDGTEQV QKLLSTVYRV
     KQRFATGHII DVLRGIDTER VQQFHHAELS TFGIGADASE AEWRAVIRQT IAQNLLTVDF
     ESFSSLQLTE LARPVLKGEQ KVKLRIYEKP VKTKRTANHS SANVQDANLS DIEKAIFAAL
     RSWRFETARA HNVPAYVIFH DATLREIAIE KPTHLNELRG LSGVGEKKLD NYGAEIIEVV
     AEFI
//