ID A0A345E4R4_9EURY Unreviewed; 615 AA.
AC A0A345E4R4;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=DU500_12560 {ECO:0000313|EMBL:AXG07186.1};
OS Haloplanus rubicundus.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Haloplanus.
OX NCBI_TaxID=1547898 {ECO:0000313|EMBL:AXG07186.1, ECO:0000313|Proteomes:UP000253273};
RN [1] {ECO:0000313|EMBL:AXG07186.1, ECO:0000313|Proteomes:UP000253273}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBA1113 {ECO:0000313|EMBL:AXG07186.1,
RC ECO:0000313|Proteomes:UP000253273};
RA Kim Y.B., Roh S.W.;
RT "Genome sequences of Haloplanus sp. CBA1113.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP031150; AXG07186.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A345E4R4; -.
DR KEGG; haj:DU500_12560; -.
DR OrthoDB; 302940at2157; -.
DR Proteomes; UP000253273; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00075; HATPase; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR PANTHER; PTHR44936:SF9; SENSOR HISTIDINE KINASE GLNK; 1.
DR PANTHER; PTHR44936; SENSOR PROTEIN CREC; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:AXG07186.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 324..374
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 421..613
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 553..573
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 615 AA; 66922 MW; FEF6E3317DB81833 CRC64;
MSLESYLPDP VRSRYALKLL GVSLLIVLLI TALTTVTVFQ VSDRVRDNQL RSVETNAELE
ARALGQWIDG KQQVVRTLSN HEGLTPVADD RTQATLTTEL DALSPETASL SIVERSPHVH
SNGTTETIVA STDSQFVGRP LSVTDANWKP TVGFNFEDTD DVILSLVYTD GDETFVALAS
PMPDGEHVLV AEYQTSVRAE RFTSAINGTD TLVLGGYTAY VLFDENESDG ITPYEGDRAN
TTIGRTILQS DPTSDIHGAV LTDTEVKGYY SVPGEKVDWV VVKEVPRSKA LAVTDRVQRD
LWLVVGIVMA GFLLIGAVIQ LGPIRSIKRL SKQGNAIAEG NLGVDIDRGD RNDEVGEVQS
AFDNIRAYVE TITEQAEALS RQSFDDDVLD ADVPGRVGES VATMHHDLQQ FITRLDVLNR
ILRHNLRNQL DVIDSHAEVL DESEHRAAIL AATETLAGLG TRARHIDHIL SKDPQPTRID
LADRIDAVLR DVETDGVTVG TSIPDDATVV TDAEILTTVL RSPLENAVEY TDSGVGVSVE
STDSGCTIEI RDDGPGIPDS ELEPLATDQE TPLQHSRGLG LWELKWGVDE LDGDLSFVTD
DGTTVVIRLP DLDST
//
