ID A0A345HI31_9ACTN Unreviewed; 504 AA.
AC A0A345HI31;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=DVK44_00180 {ECO:0000313|EMBL:AXG76355.1};
OS Streptomyces paludis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2282738 {ECO:0000313|EMBL:AXG76355.1, ECO:0000313|Proteomes:UP000253868};
RN [1] {ECO:0000313|Proteomes:UP000253868}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GSSD-12 {ECO:0000313|Proteomes:UP000253868};
RA Zhao J.;
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP031194; AXG76355.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A345HI31; -.
DR KEGG; spad:DVK44_00180; -.
DR OrthoDB; 9786919at2; -.
DR Proteomes; UP000253868; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:AXG76355.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000253868};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 205..257
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 272..490
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 504 AA; 53757 MW; DA239EABF471A3DC CRC64;
MRVPRLIRGL GGLRVRLIVA FTLVAVAGTL TTGALTFREA RNGVLQQSQD SVLKQFRDHV
NTLAPAFTLP LNQTTLDGFA ADAARAGRSQ GWRVLAVYGD LRATSVEGDD FAELTPSLRE
AATDRPVTVF QRVTKGDRSV LVMGVPVTYA PVAEGEPRRA SGLVVFLSVS QRNEQAYVDA
LVSAVQRAVL PALGLAVVLA LLAARGVLRP VRELRRAAGS MAEGRFDTRL TVHGSDELAD
LSQTFNETAS ALDRSVAELR RMEARARAFA ADVSHELRTP LAAMAAVTDV LDEDARGLDP
DTATAVRLIS QETGKLARLV DDLMEVSRFD AGAAELRPDE IDLAESLRRT LASRGWTDTV
ETELPPPGGP RVLADPRRLD VVVANLVANA LRHGAPPVRV RLYAAPERTG GPPARAVVEV
SDRGPGIPEE VLPHVFERFY KSDSARTRTE GSGLGLAIAM ENVRLHGGTL TAANRPGGGA
VFTMDIPLGP VDSAPGAPVE EDLA
//
