ID A0A345HL65_9ACTN Unreviewed; 406 AA.
AC A0A345HL65;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Protein-L-isoaspartate O-methyltransferase {ECO:0000256|ARBA:ARBA00013346};
DE EC=2.1.1.77 {ECO:0000256|ARBA:ARBA00011890};
DE AltName: Full=L-isoaspartyl protein carboxyl methyltransferase {ECO:0000256|ARBA:ARBA00031350};
DE AltName: Full=Protein L-isoaspartyl methyltransferase {ECO:0000256|ARBA:ARBA00030757};
DE AltName: Full=Protein-beta-aspartate methyltransferase {ECO:0000256|ARBA:ARBA00031323};
GN ORFNames=DVK44_06730 {ECO:0000313|EMBL:AXG77439.1};
OS Streptomyces paludis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2282738 {ECO:0000313|EMBL:AXG77439.1, ECO:0000313|Proteomes:UP000253868};
RN [1] {ECO:0000313|Proteomes:UP000253868}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GSSD-12 {ECO:0000313|Proteomes:UP000253868};
RA Zhao J.;
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. L-
CC isoaspartyl/D-aspartyl protein methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005369}.
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DR EMBL; CP031194; AXG77439.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A345HL65; -.
DR KEGG; spad:DVK44_06730; -.
DR OrthoDB; 5143400at2; -.
DR Proteomes; UP000253868; Chromosome.
DR GO; GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR000682; PCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR11579; PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11579:SF0; PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE; 1.
DR Pfam; PF01135; PCMT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:AXG77439.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000253868};
KW Transferase {ECO:0000313|EMBL:AXG77439.1}.
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 406 AA; 43674 MW; 02F28BE43D08CC68 CRC64;
MGDHRKPEPD VGEAKPPPGN PELRHRLDRA LEAERGWPAD SPWVRRAVED LPRHLFAPDR
VWVWDGSTYV PVDRTADPGR WAELVYPQPD EATVTQVTDG LATSSLSCQA VVVDMLDSLM
PEPGHRVLEL GTGAGWNAAL LAARAGPGRV TSVEVDPGLA EAARARLGAA GAEVNVVTGD
GAHGWAESAP FDRLIATYAV DEVPWAWVEQ TRPGGRIVTP WGRLGHVALT VADDGRSASG
WMQGLATFMP SRGTGQGLPW DRIRGTVPAG TAGPFQQPLR RLHDEVSLLF ALRVVLPDVR
ITTRAYDDGV SAWLHDGRAS WATLDARAGD PAVACQGGPR RLADETSRTM EKWLTAGEPS
LYDFGMTRTP DQQFIWTGDK DTGPRWTAAS GQCEAEWGGS VAGIAG
//
