ID A0A345KWV5_9CAUD Unreviewed; 608 AA.
AC A0A345KWV5;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=DNA polymerase I {ECO:0000313|EMBL:AXH47507.1};
GN Name=46 {ECO:0000313|EMBL:AXH47507.1};
GN ORFNames=SEA_HOPE4EVER_46 {ECO:0000313|EMBL:AXH47507.1};
OS Mycobacterium phage Hope4ever.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Fromanvirus.
OX NCBI_TaxID=2250300 {ECO:0000313|EMBL:AXH47507.1, ECO:0000313|Proteomes:UP000258744};
RN [1] {ECO:0000313|EMBL:AXH47507.1, ECO:0000313|Proteomes:UP000258744}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Ali M., Bermudes O., Casimir E., Chandie V., DeJesus L., Diaz K.,
RA Escobar I., Garcia J., Gildon J., Kacirani A., Kaur K., Kim Y.,
RA Lee J.-W.D., Lopez A., Mata D., Oltaci A., Palencia G., Seecharan G.,
RA Sherpa C., Smith S., Tolentino S., Urena K., Yang X., Yauri C.,
RA Golebiewska U.P., Washington J.M., Garlena R.A., Russell D.A., Pope W.H.,
RA Jacobs-Sera D., Hendrix R.W., Hatfull G.F.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; MH513971; AXH47507.1; -; Genomic_DNA.
DR Proteomes; UP000258744; Genome.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR GO; GO:0039693; P:viral DNA genome replication; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.370; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR001098; DNA-dir_DNA_pol_A_palm_dom.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR002298; DNA_polymerase_A.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10133; DNA POLYMERASE I; 1.
DR PANTHER; PTHR10133:SF27; DNA-DIRECTED DNA POLYMERASE; 1.
DR Pfam; PF00476; DNA_pol_A; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR SMART; SM00474; 35EXOc; 1.
DR SMART; SM00482; POLAc; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00023109};
KW Reference proteome {ECO:0000313|Proteomes:UP000258744};
KW Viral DNA replication {ECO:0000256|ARBA:ARBA00023109}.
FT DOMAIN 15..192
FT /note="3'-5' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00474"
FT DOMAIN 372..555
FT /note="DNA-directed DNA polymerase family A palm"
FT /evidence="ECO:0000259|SMART:SM00482"
SQ SEQUENCE 608 AA; 67490 MW; B4F60D7270B4484E CRC64;
MKQHRYQIKD ETVLVNVVEH EDDLDGFESF IRSNLRILGL DTETTDLGIY KPDFGIRLIQ
FGNPWESWVL PVERGGAFVG AAVAALQKVQ RFVIHNAAFD LQVIERTLGV PMAQMWPKVE
DTKIYSHLVD PRAYKEGGTG HKLEELTKFY IDPVTAEEVK ASMARLAKKH KTTKDKIWAL
VDLDDPDYEL YAGMDTILVS RLLGKVAPLV PESSHKLIPY EHKLAEVMSY VERTGFLLDV
DYSEKLSADM LRKAEHYTAV ARYAYGVDSV NSTEKLADGL ERTGVKIKGR TATNKRQVNA
ELLEALAEEG NALAKAAIEA KKWGSWEKTW VRNFIERRDA DDRVHPGINP LQARTGRMST
SNPSAQNLPS GDWMVRRCFL ADPGQLMVSV DYQAQELRVL AALANDRTMI RAFEEEADLH
QVTADAAGMD RKVGKMANFL TVYGGGAGKL ATNAGITFPE AKKVLDIFAA TYPGVTDLSK
SLQREAANLG YVVTPTGRRL PVDPDRGYAA LNYMVQSTSR DVTASAVLRL HEAGMTPMIR
LVIHDEVLAS VPEAEAEATA KEIGRIMEQT FRGVLINTDP EVGGRSWGAA YLKKDEQPSA
DPFLRIPA
//
