ID A0A345P8X2_9GAMM Unreviewed; 392 AA.
AC A0A345P8X2;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Acetyl-CoA C-acyltransferase {ECO:0000313|EMBL:AXI03731.1};
DE EC=2.3.1.16 {ECO:0000313|EMBL:AXI03731.1};
GN ORFNames=HYN46_13350 {ECO:0000313|EMBL:AXI03731.1};
OS Aquirhabdus parva.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Aquirhabdus.
OX NCBI_TaxID=2283318 {ECO:0000313|EMBL:AXI03731.1, ECO:0000313|Proteomes:UP000253940};
RN [1] {ECO:0000313|EMBL:AXI03731.1, ECO:0000313|Proteomes:UP000253940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HYN0046 {ECO:0000313|EMBL:AXI03731.1,
RC ECO:0000313|Proteomes:UP000253940};
RA Kim M., Yi H.;
RT "Genome sequencing of Moraxellaceae gen. HYN0046.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP031222; AXI03731.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A345P8X2; -.
DR KEGG; mbah:HYN46_13350; -.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000253940; Chromosome.
DR GO; GO:0003988; F:acetyl-CoA C-acyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR18919:SF144; ACYL-COA THIOLASE-RELATED; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW ECO:0000313|EMBL:AXI03731.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000253940};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:AXI03731.1}.
FT DOMAIN 5..262
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 269..390
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 89
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 348
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 378
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 392 AA; 40639 MW; 9E7CD02CF43CB3FB CRC64;
MSESIVIVGG ARTAMGGFQG VFANVTAPEL GATAIREAVS RAGLQPTDIQ EVIMGCVLPG
GLKQGPARQA MRKAGLPDTT GAVTINKLCG SGMKAVMQAA DMLAAGSADI VVAGGMESMS
NAPYILPKAR TGLRMGHGEV KDHMFLDGLE DAETGRLMGS FAQDMANTLS YTREQMDDFA
IRSLKRAQTA INEGYFKDEI VPVTVKGRAG DVEVVQDEQP LNAKLDKIPT LKPAFAKDGT
ITAANASSIS DGSSALVLTR ESTAKEKGLT PLARILATAS NSQHPSEFTI APVGAIAKVL
QKTGWAASDV DLWEINEAFA MVTMAAIDKY SLDAEKVNIN GGACALGHPV GSTGSRIILT
LIHALKRTGG KKGIAALCIG GGEATAVAIE LV
//
